Protein Purification
MilliporeSigma™ Calbiochem™ Lovastatin, Sodium Salt
Carboxylate form of Lovastatin that is active in whole cells and cell-free assays.
MilliporeSigma™ Calbiochem™ GGTI-2147
A cell-permeable non-thiol peptidomimetic that acts as a potent and selective inhibitor of geranylgeranyltransferase I (GGTase I).
MilliporeSigma™ Calbiochem™ Smac-N7 Peptide, Cell-Permeable
The Smac-N7 peptide is modified to be cell permeant by linking the lysine carboxyl terminal to the arginine of Antennapedia homeodomain 16-mer peptide via a proline linker.
MilliporeSigma™ Calbiochem™ Collagenase Inhibitor I
The Collagenase Inhibitor I controls the biological activity of Collagenase. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ Focal Adhesion Kinase Inhibitor III
A cell-permeable pyrazolobenzothiazinedioxide compound that targets and locks FAK in its inactive conformation, resulting in preincubation time-dependent inhibition in kinase assays and FAK autophosphorylation in human prostate cancer PC3M-luc cells (IC50
MilliporeSigma™ Calbiochem™ SU9516
A cell-permeable 3-substituted indolinone compound that displays anti-proliferative and proapoptotic properties in tumor cells.
MilliporeSigma™ Calbiochem™ HIF Inhibitor VII
A cell-permeable benzoxadiazolamine that prevents HIF-2α-HIF-β/ARNT heterodimeration by perturbing HIF-2α Per-ARNT-Sim/PAS-B domain surface β-sheet conformation via a 1:1 stoichiometric binding ( K D = 81nM), while exhibiting no affinity toward HIF-1αPAS-B
MilliporeSigma™ Calbiochem™ Gemcitabine, HCl
A bioavailable, moderately toxic, deoxyctytidine analog with anti-metabolite and anti-tumor properties
MilliporeSigma™ Calbiochem™ AKR1C3 Inhibitor
The AKR1C3 Inhibitor controls the biological activity of AKR1C3.
MilliporeSigma™ Calbiochem™ Apigenin
Induces the reversion of transformed phenotypes of v-H-ras-transformed NIH 3T3 cells at low concentration (12.5 μM).
MilliporeSigma™ Calbiochem™ Glucagon-Like Peptide 1 Receptor Agonist II
A pyrimidine small molecule that acts as a GLP-1 allosteric agonist that induces cAMP signaling in HEK293 cells expressing the GLP-1 receptor with EC50
MilliporeSigma™ Calbiochem™ RHC-80267
Selective inhibitor of DAG lipase activity in canine platelets (IC50 = 4 nM) and in a variety of mammalian cells.
MilliporeSigma™ Calbiochem™ Guanosine 3',5'-cyclic Monophosphorothioate, 8-(4-Chlorophenylthio)-, Rp-Isomer, Triethylammonium Salt
A potent, cell-permeable, and metabolically-stable inhibitor of protein kinase G Iα, Iβ, and type II.
MilliporeSigma™ Calbiochem™ Transglutaminase 2 Inhibitor II, ERW1041E
A cell-permeable, active-site directed, acyl-donor substrate competitive inhibitor of transglutaminase 2 (TG2, Ki = 11 μM).
MilliporeSigma™ Calbiochem™ NOX Inhibitor VIII, VAS3947
VAS3947, NOXi.