USP25/28 inhibitor AZ1 is a selective, orally active, noncompetitive dual inhibitor of deubiquitinases USP25 and USP28, with reported IC50 values of approximately 0.6-0.7 μM. It is supplied for research use as a solid or as a 10 mM solution in DMSO, and is typically provided at 98% purity.
- Selective dual inhibitor of USP25 and USP28
- Noncompetitive mechanism with IC50 ~0.6-0.7 μM
- Suitable for in vitro and in vivo preclinical studies
- Available as solid and 10 mM solution in DMSO
- High purity (98%) for research applications