Protein Purification
MilliporeSigma™ Calbiochem™ D-Val-Phe-Lys Chloromethyl Ketone, Dihydrochloride
Selective irreversible inhibitor of plasmin with high selectivity for plasmin (IC50 = 100 pM for human plasmin) over urokinase.
MilliporeSigma™ Calbiochem™ U-73343
A cell-permeable analog of U-73122 that acts as a very weak inhibitor of phospholipase C. Suitable as a negative control.
MilliporeSigma™ Calbiochem™ DUB Inhibitor V, PR-619
The DUB Inhibitor V, PR-619 controls the biological activity of DUB. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ β-Catenin/Tcf Inhibitor V, BC21
The β-Catenin/Tcf Inhibitor V, BC21, also referenced under CAS 691005-38-6, controls the biological activity of β-Catenin/Tcf. This small molecule/inhibitor is primarily used for Biochemicals applications.
MilliporeSigma™ Calbiochem™ Caspase Inhibitor VI
Z-VAD-FMK, CAS 161401-82-7, is an irreversible pan caspase inhibitor. Does not require pretreatment with esterase for in vitro studies.
MilliporeSigma™ Calbiochem™ CFTR Inhibitor II, GlyH-101
CFTR Inhibitor II, GlyH-101, CAS 328541-79-3, is a cell-permeable potent, selective and reversible open-channel blocker of CFTR (Ki = 4.3 μM in CFTR-expressing FRT cells).
MilliporeSigma™ Calbiochem™ Cathepsin L Inhibitor I
The Cathepsin L Inhibitor I, also referenced under CAS 108005-94-3, controls the biological activity of Cathepsin L. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ Troglitazone
A α-tocopherol (vitamin E) moiety containing thiazolidinedione class of insulin-sensitizer that acts as an activator of peroxisome proliferator-activated receptors γ (PPARγ).
MilliporeSigma™ Calbiochem™ WHI-P180
A potent inhibitor of lgE-mediated mast cell responses to allergens in vitro and in vivo.
MilliporeSigma™ D-Tube™ Dialyzer Maxi, MWCO 6-8 kDa
Used for dialysis and electroelution of proteins, RNA, DNA, and oligonucleotides from polyacrylamide or agarose gels
MilliporeSigma™ Novagen™ Ni-NTA HisBind™ Resin
Used for rapid one-step purification of proteins.
MilliporeSigma™ Calbiochem™ TACE Substrate IV, Fluorogenic
An internally-quenched fluorogenic decapeptide substrate that is useful for continuous monitoring of TACE activity and high-throughput screening of TACE inhibitors (kcat =
MilliporeSigma™ Calbiochem™ Triptolide, Tripterygium wilfordii
A novel diterpene triepoxide isolated from the Chinese herb Tripterygium wilfordii that acts as a potent immunosuppressant and anti-inflammatory agent.
MilliporeSigma™ Calbiochem™ UCH-L1 Inhibitor
The UCH-L1 Inhibitor, also referenced under CAS 668467-91-2, controls the biological activity of UCH-L1. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Novagen™ Factor Xa Cleavage Capture Kit
Designed for specific cleavage of fusion proteins.