Protein Purification
Creative Biomart Complement activator blocker-2 Protein
MLN2222 is a novel, proprietary recombinant protein that blocks both the C3 and C5 convertases, which are essential components of the complement activation pathway.
Cell Signaling Technology Phosphatase Inhibitor Cocktail (100X) 1 ml
Phosphatase Inhibitor Cocktail (100X) 1 ml
Enzo Life Sciences Biotinyl-DEVD-CHO (5mg)
Reversible inhibitor of caspase-3 and -7. Useful for the purification or extract depletion of caspase-3 in conjunction with streptavidin conjugates. Alternative name: Caspase-3 inhibitor (aldehyde), Caspase-7 inhibitor (aldehyde), CPP32 affinity reagent. Formula: C28H42N6O12S. MW: 686.7. Purity: ≥99% (HPLC). Appearance: White powder. Formulation: Lyophilized. Solubility: Soluble in 50% acetic acid with agitation (1mg/ml). Long Term Storage: -20°C. Handling: Packaged under inert gas.
AG Scientific Inc Protease Inhib VII for His Tag
Protease Inhibitor Cocktail VII (for His Tag Sequences) is specially formulated mixture of five protease inhibitors with broad specificity for the inhibition of cysteine, serine, aspartic, thermolysin-like proteases and aminopeptidases. Recommended for purification of proteins containing His tag sequences. 1 mL is recommended for about 10 g of cells. Each vial contains: 100 mM AEBSF HCl 5 mM Bestatin 1.5 mM E-64 2 mM Pepstatin A 200uM Phosphoramidon disodium salt
Selleck Chemical LLC Atazanavir Sulfate 10mg 229975-97-7 BMS-232632
Atazanavir Sulfate (BMS-232632) is a HIV protease inhibitor with Ki of 2.66 nM in a cell-free assay. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Enzo Life Sciences Anabaenopeptin A (100µg)
Anabaenopeptins are a highly diverse group of bioactive peptides produced by several genera of cyanobacteria such as Anabaena, Planktothrix, Microcystis and Nodularia. These peptides are commonly detected in cyanobacterial blooms along with the well known microcystins. Unique cyclic peptides where lysine is conserved in position 2 and cyclisation is achieved by linkage of the lysine to the C-terminal amino acid. In addition the side chain of a single amino acid is attached via a ureido bond. Bioactive peptides originally isolated from Anabaena flos-aquae NRC 525-17 where they were shown to be non-toxic in mice but had dose dependant relaxations in rat aortic preparations with endothelium precontracted with 0.1µM norpinephrine. Anabaenopeptins inhibit protein phosphatase. Purity: ≥95% (HPLC). Appearance: Pale powder or an oil (film), depending on the lot. Solubility: Soluble in methanol. Long Term Storage: -20°C.
Cayman Chemical PI3-Kinase α Inhibitor 2 (hydrochloride), Purity: ≥98%, CAS: 1188890-32-5, 1 mg
An inhibitor of PI3K p110α (IC50 = 2 nM in an enzyme assay); selective for p110α over p110β, p110γ, and PI3K C2β (IC50s = 16, 660, and 220 nM, respectively); inhibits mTOR (IC50 = 49 nM); inhibits proliferation in A375 melanoma cells (IC50 = 0.58 μM)
Cayman Chemical ASK1 Inhibitor 10, Purity: ≥95%, CAS: 1005775-56-3, 5 mg
An orally bioavailable inhibitor of ASK1 (IC50 = 14 nM); selective for ASK1 over ASK2 (IC50 = 510 nM) as well as MEKK1, TAK-1, IKKβ, ERK1, JNK1, p38α, GSK3β, PKCθ, and B-RAF (IC50s = >10,000 nM for all); inhibits streptozotocin-induced increases in JNK and p38 phosphorylation in INS-1 pancreatic β cells in a concentration-dependent manner
Cayman Chemical Heat Shock Protein Inhibitor II, Purity: ≥98%, CAS: 1859-42-3, 10 mg
The active form of Hsp inhibitor I; a benzylidene lactam compound; prevents the synthesis of inducible Hsps, including Hsp105, Hsp72, and Hsp40; decreases Hsp72 synthesis in vivo; at 100 µM, inhibits the development of thermotolerance in COLO 320 DM cells; reduces thermotolerance of tumors in SCC VII tumor-containing mice; in combination with AmB increases susceptibility of AmB-susceptible (MICs = 0.058 versus 0.27 µg/ml for combined and AmB alone, respectively) and AmB-resistant (MICs = 21.33 versus >32 µg/ml for combined and AmB alone, respectively) strains of A. fumigatus
Cayman Chemical Aurora Kinase Inhibitor III, Purity: ≥98%, CAS: 879127-16-9, 1 mg
A potent inhibitor of Aurora A kinase (IC50 = 42 nM); selective for Aurora A over BMX, BTK, IGF-1R, c-Src, TRKB, SYK, and EGFR (IC50s = 386, 3,550, 591, 1,980, 2,510, 887, and >10,000 nM, respectively)
Revvity Health Sciences Inc Tag-lite Adenosine A1 receptor Frozen & Labeled Cells, 200 Assay Points
Tag-lite Adenosine A1 receptor Frozen & Labeled Cells, 200 Assay Points
Medchemexpress LLC Brm/Brg1 ATP inhibitor-1 | 2270879-17-7 | 99.7% | 10 MG
BRM/BRG1 ATP inhibitor-1 is an orally active, allosteric small-molecule inhibitor that selectively targets the ATPase activity of BRM (SMARCA2) and BRG1 (SMARCA4). It demonstrates sub-nanomolar potency and has shown anticancer activity in preclinical studies, making it useful for epigenetic and chromatin remodeling research.
- Potent allosteric dual inhibitor of BRM and BRG1 ATPase activity.
- Sub-nanomolar potency (IC50 < 0.005 μM) for both targets.
- High purity suitable for biochemical and cell-based assays.
- Available in solid and solution formats, including 10 mg solid and 10 mM in DMSO.
- Recommended storage conditions preserve stability (powder: -20°C; in solvent: -80°C).
CPC Scientific DABCYL-GABA-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Glu(EDANS)-Ala-Lys-NH2 (trifluoroacetate salt) 1MG
Selective fluorogenic matrix metalloproteinase (MMP) substrate with the following Kcat/Km value for MMP-3 (Stromelysiin-1) is 29.0 M-1s-1, for MMP-13 13.0 M-1s-1, and for MMP-9 7.5 M-1s-1 (at pH = 7.5, 25°C). The fluorescence increase is measured using an wavelength of 360 nm and an emission wavelength of 490 nm. No activity against this substrate could be measured with MMP-1, MMP-7, and MMP-8. ONE-LETTER SEQUENCE: Dabcyl-GABA-RPKPVE-Nva-WR-Glu(EDANS)-AK-NH2MOLECULAR FORMULA: C99H144N28O20S1MOLECULAR WEIGHT:2078.44STORAGE CONDITIONS: -20 5C, CAS REGISTRY NUMBER: [202273-56-1], RESEARCH AREA: CancerREFERENCES: Beekman, B., et al., 1997. FEBS Lett 418, 305.
Cayman Chemical IRAK Inhibitor 1, Purity: ≥98%, CAS: 1042224-63-4, 10 mg
An IRAK4 inhibitor (IC50 = 35 nM); selective for IRAK4 over JNK1 and JNK2 at 10 µM; prevents increases in TNF-α and IL-12p40 levels in M. bovis-infected THP-1 cells at 1 µM