Protein Purification
MilliporeSigma™ Calbiochem™ InSolution™ Necrostatin-1
A cell-permeable, potent, and selective blocker of necroptosis (EC50 = 494nM in FADD-deficient Jurkat cells treated with TNF-α), a nonapoptotic necrotic cell death pathway mediated by death-domain receptors (DRs) that offers neuroprotection in a murine model of ischemic brain inj
MilliporeSigma™ Calbiochem™ Pepstatin A, Penetratin
A Pepstatin A that is ≈75% less potent against Cathespins D/E than PepA in cell-free assays.
MilliporeSigma™ Calbiochem™ Dantrolene, Sodium Salt
A cell-permeable blocker of intracellular calcium release from the sarcoplasmic reticulum that acts by binding to the ryanodine receptor.
MilliporeSigma™ Calbiochem™ Triptolide, Tripterygium wilfordii
A novel diterpene triepoxide isolated from the Chinese herb Tripterygium wilfordii that acts as a potent immunosuppressant and anti-inflammatory agent.
MilliporeSigma™ Calbiochem™ CA-074
CA-074, also referenced under CAS 134448-10-5, modulates the biological activity of cathepsin B. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ ER Export Inhibitor II, FLI-06
A cell-permeable compound that reversibly blocks cellular glycosylation and surface expression of Notch, APP, Klotho by blocking events prior to cargo assembly at the ER exit sites.
MilliporeSigma™ Calbiochem™ InSolution™ IKK-2 Inhibitor IV
The InSolution™ IKK-2 Inhibitor IV controls the biological activity of IKK-2. This small molecule/inhibitor is primarily used for Inflammation/Immunology applications.
MilliporeSigma™ Calbiochem™ KMO Inhibitor I, Ro 61-8048
The KMO Inhibitor I, Ro 61-8048, also referenced under CAS 199666-03-0, controls the biological activity of KMO. This small molecule/inhibitor is primarily used for Neuroscience applications.
MilliporeSigma™ Calbiochem™ Reboxetine Mesylate
A potent and selective inhibitor of noradrenalin uptake (Ki values ar
MilliporeSigma™ Calbiochem™ MAS 7
A cell-permeable, amphiphilic, mastoparan analog with five-fold greater potency than Mastoparan.
MilliporeSigma™ Calbiochem™ Ubiquitin Isopeptidase Inhibitor I, G5
The Ubiquitin Isopeptidase Inhibitor I, G5, also referenced under CAS 108477-18-5, controls the biological activity of Ubiquitin Isopeptidase. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ SecinH3
A cell-permeable triazolo compound that acts as a Sec7 domain-binding, selective antagonist against cytohesin family small GEFs.
MilliporeSigma™ Calbiochem™ Phosphoramidon, Disodium Salt
Inhibits some metalloendopeptidases.
MilliporeSigma™ Calbiochem™ U-73343
A cell-permeable analog of U-73122 that acts as a very weak inhibitor of phospholipase C. Suitable as a negative control.
MilliporeSigma™ Calbiochem™ Dynamin Inhibitor III, Phthaladyn-23
A cell-permeable phthalimide compound that is reported to inhibit dynamin GTPase activity (IC50 =