Protein Purification
Abcam GSK-J1, H3K27 histone demethylase inhibitor, 50MG
MW 389.4 Da, Purity >99%. Potent and selective H3K27 histone demethylase inhibitor (IC₅₀ = 60 nM, JMJD3). Inhibits UTX. Some activity for the H3K4me3/2/1 demethylases Jarid1b and Jarid1c (IC₅₀ values are 950 nM and 1.76 μM, respectively). No significant inhibitory activity against 100 protein kinases at a concentration of 30 μM. Anti-inflammatory effects.
The product is subject to the following: Abcam Restricted Use Statement
Abcam WHI-P131 hydrochloride, JAK3 inhibitor, 25MG
MW 297.31 Da, Purity >98%. Cell-permeable Janus kinase 3 (JAK3) inhibitor (IC₅₀ values of 9.1 μM and 78 μM for human and mouse recombinant proteins respectively). Selective versus JAK1, JAK2, SYK, BTK and LYN tyrosine kinases.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Vatalanib dihydrochloride, VEGFR tyrosine kinase inhibitor, 10MG
MW 419.7 Da, Purity >98%. Cell-permeable, potent, selective inhibitor of the VEGFR tyrosine kinases VEGFR-1 (Flt-1) and VEGFR-2 (FLK-1/KDR) (IC₅₀ values are 77 nM and 37 nM respectively). Weaker inhibitor of other tyrosine kinases including PDGFR-β, c-KIT, VEGFR-3 (FLT-4) and c-FMS (IC₅₀ values are 580 nM, 730 nM, 660 nM and 1.4 μM respectively). Inactive against EGFR, c-SRC, v-ABL, and protein kinase Cα (IC₅₀ > 10 μM). Induces dose-dependent inhibition of VEGF and PDGF-induced angiogenesis in a growth factor implant model.
The product is subject to the following: Abcam Restricted Use Statement
![Biolegend Brilliant Violet 750™ anti-human IL-2 [MQ1-17H12]; Isotype: Rat IgG2a κ; Reactivity: Human; Apps: ICFC; Size: 25 tests](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502557573.png-250.jpg)
Biolegend Brilliant Violet 750™ anti-human IL-2 [MQ1-17H12]; Isotype: Rat IgG2a κ; Reactivity: Human; Apps: ICFC; Size: 25 tests
Brilliant Violet 750™ anti-human IL-2 [MQ1-17H12]; Isotype: Rat IgG2a κ; Reactivity: Human; Apps: ICFC; Size: 25 tests
Abcam FAK Inhibitor 14 (mM/ml), FAK autophosphorylation inhibitor, 20MM_ML
MW 174.63 Da. Selective focal adhesion kinase (FAK) autophosphorylation inhibitor (IC₅₀ = 1 μM). No significant activity at other kinases including EGFR, PDGFR and IGF-RI. Increases cell detachment and inhibits cell adhesion in cancer cells. Anticancer agent. Active in vivo and in vitro.
The product is subject to the following: Abcam Restricted Use Statement
Abcam CRT0066101 (mM/ml), protein kinase D inhibitor, 20MM_ML
MW 411.33 g/mol, Purity >99%. Potent and selective protein kinase D inhibitor (IC₅₀ values are 1, 2 and 2.5 nM at PKD1, PKD3 and PKD2, respectively). Reduces proliferation of pancreatic cancer cells. Orally active. Antitumor agent. Active in vivo and in vitro.
The product is subject to the following: Abcam Restricted Use Statement
Echelon Biosciences Research Labs Caspase 3 Substrate - 5 mg,
Caspase 3 Substrate - 5mg , Ac-Asp-Glu-Val-Asp-4-methoxy-2-naphthylamide Category/Application: Enzyme Substrates This item is non returnable
American Research Products Inc ACETYLCHOLINESTERASE INHIBITIO
5000265574 ACETYLCHOLINESTERASE INHIBITIO
Cayman Chemical ADAMTS-5 InhIbItr 1mg
An inhibitor of ADAMTS-5 (aggrecanase-2; IC50 = 1.1 µM) with 40-fold selectivity over ADAMTS-4 (aggrecanase-1)
STEMCELL Technologies EasySep™ Human FITC Positive Selection Kit II, For processing: 1 x 10^9 cells
The EasySep™ Human FITC Positive Selection Kit II is designed to isolate cells that are labeled with FITC-conjugated antibodies. Desired cells are targeted with antibody complexes recognizing FITC and dextran-coated magnetic particles. Labeled cells are separated using an EasySep™ magnet without the use of columns. Cells of interest remain in the tube while unwanted cells are poured off.This product replaces the EasySep™ Human FITC Positive Selection Kit (Catalog #18552).
STEMCELL Technologies EasySep™ Mouse CD45 Positive Selection Kit, For processing: 2 x 10^9 cells
The EasySep™ Mouse CD45 Positive Selection Kit is designed to isolate CD45 cells from single-cell suspensions of splenocytes, lung, or other tissues by positive selection. Desired cells are targeted with antibody complexes recognizing CD45 and dextran-coated magnetic particles. Labeled cells are separated using an EasySep™ magnet without the use of columns. Cells of interest remain in the tube while unwanted cells are poured off.
STEMCELL Technologies EasySep™ Human Eosinophil Isolation Kit, For isolating: 1 x 10^9 cells
The EasySep™ Human Eosinophil Isolation Kit is designed to isolate eosinophils from a polymorphonuclear cell-rich fraction of peripheral blood by negative selection. Unwanted cells are targeted for removal with Tetrameric Antibody Complexes recognizing non-eosinophils and magnetic particles. Labeled cells are separated using an EasySep™ magnet without the use of columns. Desired cells are poured off into a new tube. The kit is compatible with cells prepared using either Lymphoprep™ (Catalog #07801) centrifugation (preferred for higher cell purities) or HetaSep™ (Catalog #07906) sedimentation (preferred for faster, lysis-free sample processing).This product replaces the EasySep™ Human Eosinophil Enrichment Kit (Catalog #19256) for even faster cell isolations.
Agilent Technologies High Sensitivity Protein 250 Labeling Kit
Reagents for labeling reaction only. Sufficient for 100 samples.
MAGIC BIOPROCESSING MAGic™Beads ACT 10mL
MAGic™ Beads ACT are super-paramagnetic porous beads designed for in-house coupling of ligands containing amino groups or thiols. Proteins, peptides, and other biomolecules can be covalently attached using a simple, sustainable process, all under physiological conditions and at room temperature, without hazardous reagents or organic solvents. Once coupled, the beads are ready for affinity purification or immunoprecipitation. Supplied as a 10% slurry, MAGic™ Beads ACT offer a versatile platform for developing your own magnetic bead-based applications.