Protein Purification
MilliporeSigma™ Calbiochem™ RAD51-Stimulatory Compound-1, RS-1
A cell-permeable sulfonamido-benzamide-based allosteric regulator that stimulates DNA binding and recombinase activities of hRAD51 by locking hRAD51 in an active conformation without affecting its active site ATP hydrolysis.
MilliporeSigma™ Calbiochem™ Sodium 4-Phenylbutyrate
A novel anti-neoplastic agent and transcriptional regulator.
MilliporeSigma™ Calbiochem™ Shikonin
A naphthoquinone found in the Chinese herb Shiunko.
MilliporeSigma™ Calbiochem™ Spermidine, Trihydrochloride
Polyamine that plays an important role in the regulation of cellular proliferation and differentiation.
MilliporeSigma™ Calbiochem™ eIF4E/eIF4G Interaction Inhibitor, 4EGI-1
eIF4E/eIF4G Interaction Inhibitor, 4EGI-1, CAS 315706-13-9, is a cell-permeable compound that reversibly binds eIF4E (KD = 25 μM) and disrupts eIF4E/eIF4G complex formation.
MilliporeSigma™ Calbiochem™ Elastase Substrate I, Colorimetric
A specific chromogenic substrate for human neutrophil elastase.
MilliporeSigma™ Calbiochem™ ERK Inhibitor
The ERK Inhibitor, also referenced under CAS 1049738-54-6, controls the biological activity of ERK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Autotaxin Inhibitor III, PF-8380
The Autotaxin Inhibitor III, PF-8380, also referenced under CAS 1144035-53-9, controls the biological activity of Autotaxin. This small molecule/inhibitor is primarily used for Membrane applications.
Thermo Scientific™ Pierce™ Protein G IgG Plus Orientation Kit, 2 mL
Bind and covalently immobilize antibodies to create a reusable affinity purification column with high binding capacity with Protein A or G agarose columns and DSS crosslinker.
MilliporeSigma™ Calbiochem™ SKP2 E3 Ligase Inhibitor IV
A cell-permeable inhibitor of SKP2-dependent p27Kip1 ubiquitination. Selectively induces the accumulation SCFSKP2 substrates in multiple myeloma RPMI 8226 cells.
MilliporeSigma™ Calbiochem™ D-erythro-Sphingosine, N,N-Dimethyl-
A cell-permeable and reversible inhibitor of protein kinase C (PKC; IC50 = 12 μM) and stimulates Src kinase activity.
MilliporeSigma™ Calbiochem™ Mevastatin
An antibiotic that acts as a potent inhibitor of HMG-CoA reductase, thus suppressing Ras farnesylation.
MilliporeSigma™ Calbiochem™ GP Antagonist-2A
The GP Antagonist-2A controls the biological activity of GP. This small molecule/inhibitor is primarily used for Neuroscience applications.
MilliporeSigma™ Calbiochem™ Troponin Activator, CK-2017357
Directly and selectively binds to the troponin complex in fast skeletal muscle (Kd = 40 nM) and sensitizes it to calcium.
MilliporeSigma™ Calbiochem™ PKR/PERK Activator, DHBDC
A cell permeable dual activator of protein kinase R (PKR) and protein kinase R like kinase (PERK). Induces the phosphorylation of IκBα and thereby activates NF-κB pathway.