Protein Purification
Cayman Chemical FurIn InhIbItr ItrIfluoroa 1mg
A selective, irreversible, and cell-permeable competitive inhibitor of proprotein convertases, including furin/SPC1 (Ki = ~1 nM), SPC2/PC2 (Ki = 0.36 nM), SPC3/PC1/PC3 (Ki = 2.0 nM), SPC4/PACE4 (Ki = 3.6 nM), SPC6/PC5/PC6, and SPC7/LPC/PC7/PC8 (Ki = 0.12 nM)
CPC Scientific MCA-Pro-Leu-Ala-Nva-Dap(DNP)-Ala-Arg-NH2 (trifluoroacetate salt) 0.5MG
Sensitive substrate for continuous assays and in situ determination of the matrix metalloproteinase activity. When cleaved at the Gly-Leu bond it separates the highly fluorescent Mca group from the efficient 2,4-dinitrophenyl quencher and results in the increase of fluorescence intensity. The kcat/km value for the punctuated metalloproteinase (MMP-7) and for gelatinase (MMP-2), e.g., are 1.7 x 105 and 6.3 x 105 M-1s-1, respectively. ONE-LETTER SEQUENCE: Mca-PLA-Nva-Dap(Dnp)-AR-NH2MOLECULAR FORMULA: C49H68N14O15MOLECULAR WEIGHT:1093.16STORAGE CONDITIONS: -20 5C, CAS REGISTRY NUMBER: [256394-92-0], SYNONYMS: Mca-Pro-Leu-Ala-Nva-Dap(Dnp)-Ala-Arg-NHRESEARCH AREA: CancerREFERENCES: G. Murphy, et al., J. Biol. Chem. 269, 6632 (1994)
Hampton Research HR2-909-05/SaltRx 2 #05 (E05), 185 ml - 1.0 M Sodium phosphate monobasic monohydrate, Potassium phosphate dibasic / pH 5.0
HR2-909-05/SaltRx 2 #05 (E05), 185 ml - 1.0 M Sodium phosphate monobasic monohydrate, Potassium phosphate dibasic / pH 5.0. Please note items from this supplier are non-returnable.
Hampton Research SALTRX 2 NO27 185ML
HR2-909-27/SaltRx 2 #27 (G03), 185 ml - 1.0 M Magnesium sulfate hydrate, 0.1 M Tris pH 8.5. Please note items from this supplier are non-returnable.
Hampton Research SALTRX 2 NO33 185ML
HR2-909-33/SaltRx 2 #33 (G09), 185 ml - 0.7 M Ammonium tartrate dibasic, 0.1 M Tris pH 8.5. Please note items from this supplier are non-returnable.
CPC Scientific MCA-Pro-Leu-Gly-Leu-Dap-Ala-Arg-NH2 (trifluoroacetate salt) 1MG
ONE-LETTER SEQUENCE: Mca-PLGL-Dap-AR-NH2MOLECULAR FORMULA: C43H66N12O11MOLECULAR WEIGHT:927.1STORAGE CONDITIONS: -20 5CRESEARCH AREA: CancerREFERENCES: C.G. Knight, et al. FEBS Lett. 296, 263 (1992)
CPC Scientific DABCYL-GABA-Pro-Gln-Gly-Leu-Glu(EDANS)-Ala-Lys-NH2 (trifluoroacetate salt) 0.5MG
Highly soluble fluorogenic matrix metalloproteinase (MMP) substrate with the following kcat/km values (at pH 7.6, 37C): 619.0 M-1s-1 for MMP-2, 209.0 M-1s-1 for MMP-9, 40.0 M-1s-1 for MMP-3, 21.0 M-1s-1 for MMP-1. The fluorescence increase is measured using an wavelength of 340 nm and emission wavelength of 485 nm. The relative high emission wavelength of EDANS allows convenient measurement of MMP activity in complex biological media like synovial fluid and culture medium.SEQUENCE: DABCYL-GABA-Pro-Gln-Gly-Leu-Glu(EDANS)-Ala-Lys-NH2 (trifluoroacetate salt)ONE-LETTER SEQUENCE: Dabcyl-GABA-PQGL-Glu(EDANS)-AK-NH2MOLECULAR FORMULA: C63H88N16O14S1MOLECULAR WEIGHT: 1325.56STORAGE CONDITIONS: -20 5 CCAS REGISTRY NUMBER: [193475-71-7]SYNONYMS: TNO211, DABCYL--Abu-Pro-Gln-Gly-Leu-Glu(EDANS)-Ala-Lys-NHRESEARCH AREA: CancerREFERENCES:B. Beekman, et al., FEBS Lett, 390, 221 (1996)SKU(
HORIZON DISCOVERY BIOSCIENCES LIMITED INDUCIBLE HUMAN FANCM HEF1A-TU
NC3425165 INDUCIBLE HUMAN FANCM HEF1A-TU
Selleck Chemical LLC AC480 (BMS-599626) 5mg 714971-09-2
AC480 (BMS-599626) is a selective and efficacious inhibitor of HER1 and HER2 with IC50 of 20 nM and 30 nM, ~8-fold less potent to HER4, >100-fold to VEGFR2, c-Kit, Lck, MET etc. Phase 1. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Hampton Research HR2-996-73/Silver Bullets #73 (G1), 0.25 ml
HR2-996-73/Silver Bullets #73 (G1), 0.25 ml. Please note items from this supplier are non-returnable.
Hampton Research HR2-996-74/Silver Bullets #74 (G2), 0.25 ml
HR2-996-74/Silver Bullets #74 (G2), 0.25 ml. Please note items from this supplier are non-returnable.
Hampton Research HR2-996-67/Silver Bullets #67 (F7), 0.25 ml
HR2-996-67/Silver Bullets #67 (F7), 0.25 ml. Please note items from this supplier are non-returnable.