Protein Purification
Novus Biologicals™ Vismodegib Hedgehog inhibitor
May be dissolved in DMSO (200 mg/mL); or ethanol (10 mg/mL, warm)
MilliporeSigma™ Calbiochem™ (-)-Cytisine
A potent agonist selective for neuronal nAChRs (Ki = 2, 5890, 480, 329, and 492nM at α4β2, α7, α3β4, α6/α4β4, α1β1γδ, respective
MilliporeSigma™ Calbiochem™ Nrf2 Activator II, AI-1
The Nrf2 Activator II, AI-1, also referenced under CAS 75483-04-4, modulates the biological activity of Nrf2. This small molecule/inhibitor is primarily used for Biochemicals applications.
MilliporeSigma™ Calbiochem™ PknG Inhibitor
The PknG Inhibitor, also referenced under CAS 329221-38-7, controls the biological activity of PknG. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ InSolution™ Purmorphamine
Purmorphamine is a cell-permeable purine compound that induces osteoblast differentiation in C3H10T1/2 multipotent mesenchymal progenitor cells.
MilliporeSigma™ Calbiochem™ AMPK Activator V, Ampkinone
The AMPK Activator V, Ampkinone modulates the biological activity of AMPK. This small molecule/inhibitor is primarily used for Biochemicals applications.
MilliporeSigma™ Calbiochem™ Mitochondrial Pyruvate Carrier Inhibitor, UK5099
A cell-permeable α-cyanocinnamate compound that acts as a rapid, active site thiol modifying, time-dependent and non-competitive inhibitor of bi-directional pyruvate transport across plasma membranes in yeast, bacteria, Drosophila, and humans (IC50 = 50nM in rat heart mitochondria; Ki ≤ 1μM) with excellent selectivity over monocarboxylates and anions.
MilliporeSigma™ Calbiochem™ Histone Deacetylase Inhibitor III
The Histone Deacetylase Inhibitor III, also referenced under CAS 251456-60-7, controls the biological activity of Histone Deacetylase. This small molecule/inhibitor is primarily used for Cell Structure applications.
MilliporeSigma™ Calbiochem™ InSolution™ SB 202190
A potent and cell-permeable inhibitor of p38 MAP kinase
MilliporeSigma™ Calbiochem™ PD 150606
A cell-permeable, non-competitive, selective non-peptide calpain inhibitor [Ki = 210 nM for calpain-1 and 370 nM for calpain-2.
MilliporeSigma™ Calbiochem™ Ubiquitin E1 Inhibitor, PYR-41
The Ubiquitin E1 Inhibitor, PYR-41 controls the biological activity of Ubiquitin E1. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ InSolution™Blebbistatin, Racemic
InSolution™Blebbistatin, Racemic, is a 50mm in 90% DMSO. A cell-permeable, selective, and reversible inhibitor of nonmuscle myosin II. Blocks cell blebbing and disrupts cell migration and cytoKinesis.
MilliporeSigma™ Calbiochem™ Polo-like Kinase Inhibitor IV, SBE13
The Polo-like Kinase Inhibitor IV, SBE13, also referenced under CAS 775294-82-1, controls the biological activity of Polo-like Kinase. This small molecule/inhibitor is primarily used for Phosphorylation and Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ PD 174265
A potent, cell-permeable, reversible, ATP-competitive and selective inhibitor of EGF receptor (EGFR) tyrosine kinase activity (IC50 = 450 pM).
MilliporeSigma™ Calbiochem™ Meloxicam
A cell-permeable, non-steroidal anti-inflammatory drug (NSAID) of the oxicam family which preferentially inhibits the inducible isoform of COX-2 (IC50 = 4.7 μM) relative to COX-1 (IC50 = 36.6 μM).