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TL8-506 is a benzoazepine compound, analog of the Toll-like receptor 8 (TLR8) agonist VTX-2337. TL8-506 activates TLR8 more potently than the imidazoquinoline R848 (TLR7/8) and the thiazoquinolone CL075 (TLR8/7).
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Mitochondria/cytosol fractionation kit provides a unique formulation of reagents for the effective isolation of highly enriched mitochondrial fractions from the cytosolic fraction of mammalian cells, including both apoptotic and non-apoptotic cells. - Cited in over 110 publications - Isolates mitochondrial and cytosolic fractions for studying apoptotic pathways and signal transduction - Simple and easy procedure for fractionation - Suitable for detecting translocation of factors between fractions via Western blotting (WB), ELISA, or other assays
XK empty columns are designed for liquid chromatography at low to medium pressure. The user-friendly design ensures trouble-free operation with fittings for direct connection to A„KTA design instruments or other high-performance liquid chromatography systems. The product family is based on a robust design for high reproducibility and accurate results. XK columns are compatible with aqueous SOLUTIONons and most organic solvents used in liquid chromatography of macromolecules.
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XK empty columns provide reliable and reproducible separations. The tube material is of borosilicate glass which allows for visual inspection of the media bed. The columns are made of biocompatible materials that exhibit excellent chemical resistance. A broad range of column dimensions makes XK columns suitable for many different purification needs. Column packing can be performed using either a packing reservoir or an extra column tube attached with a packing connector. The QuickLock mechanism of the adapter shaft facilitates rapid and easy movement of the adapter simplifying adjustments of the bed height disassembly and cleaning. The design of the adapter plunger gives a uniform flow which maintains the integrity of the packed bed during operations. An extensive range of spare parts is available facilitating maintenance.
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The EasySep™ Mouse CD117 (cKIT) Positive Selection Kit is designed to isolate CD117+ cells from single-cell suspensions of bone marrow by positive selection. The cocktail contains a combination of PE-labeled antibodies that is directed against CD117, which are then recognized by antibody complexes that are directed against PE and dextran. Labeled cells are bound to magnetic particles and separated using an EasySep™ magnet without the use of columns. Cells of interest remain in the tube while unwanted cells are poured off.
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