Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ SB 202190, Hydrochloride
A water-soluble form of the potent p38 MAP kinase inhibitor SB 202190.
MilliporeSigma™ Calbiochem™ Phosphatase Inhibitor Cocktail Set II
A cocktail of five phosphatase inhibitors for the inhibition of acid and alkaline phosphatases as well as protein tyrosine phosphatases (PTPs). Suitable for use with cell lysates and tissue extracts.
MilliporeSigma™ Calbiochem™ Mitochondrial Pyruvate Carrier Inhibitor, UK5099
A cell-permeable α-cyanocinnamate compound that acts as a rapid, active site thiol modifying, time-dependent and non-competitive inhibitor of bi-directional pyruvate transport across plasma membranes in yeast, bacteria, Drosophila, and humans (IC50 = 50nM in rat heart mitochondria; Ki ≤ 1μM) with excellent selectivity over monocarboxylates and anions.
MilliporeSigma™ Calbiochem™ ICMT Inhibitor
The ICMT Inhibitor controls the biological activity of ICMT. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ NG,NG'-Dimethyl-L-arginine, Dihydrochloride
Cell permeable. Endogenous inhibitor of nitric oxide synthesis in vitro and in vivo. Does not exhibit any significant inhibitory effect on NOS activity.
MilliporeSigma™ Calbiochem™ Benztropine
An antagonist of muscarinic M1 and M3 receptors that induces robust differentiation of oligodendrocytes precursor cell differentiation (EC50 = 500nM) and promotes myelination.
MilliporeSigma™ Calbiochem™ Prodigiosin Serratia marcescens
A cell-permeable tripyrrole alkaloid compound that displays immunosuppressive and anti-tumor properties irrespective of p53 status and multidrug resistance.
MilliporeSigma™ Calbiochem™ Wnt Agonist
The Wnt Agonist, also referenced under CAS 853220-52-7, controls the biological activity of Wnt. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ mTOR Kinase Inhibitor II, WYE-354
The mTOR Kinase Inhibitor II, WYE-354, also referenced under CAS 1062169-56-5, controls the biological activity of mTOR. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ KB-R7943
A cell-permeable isothiourea derivative that inhibits the influx/reverse mode of Na+/Ca2+ exchangers (NCX; IC50
MilliporeSigma™ Calbiochem™ LSD1 Inhibitor VII, SP-2509
A cell-permeable, potent, selective, reversible inhibitor of Lysine-Specific Demethylase 1 (LSD1; IC50 = 13 nM; Ki = 31 nM).
MilliporeSigma™ Calbiochem™ Glucokinase Activator, Cpd A
The Glucokinase Activator, Cpd A, also referenced under CAS 603108-44-7, modulates Glucokinase. This small molecule/inhibitor is primarily used for Activators/Inducers applications.
MilliporeSigma™ Calbiochem™ MMP-13 Inhibitor
The MMP-13 Inhibitor, also referenced under CAS 544678-85-5, controls the biological activity of MMP-13. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ IRE1 Inhibitor IV, KIRA6
KIRA6, IRE1a Kinase Inhibitor.
MilliporeSigma™ Calbiochem™ Elastase Substrate I, Colorimetric
A specific chromogenic substrate for human neutrophil elastase.