Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ Pyruvate Kinase Activator
The Pyruvate Kinase Activator controls the biological activity of Pyruvate Kinase. This small molecule/inhibitor is primarily used for Activators/Inducers applications.
MilliporeSigma™ Calbiochem™ Fucosyltransferase Inhibitor, 2F-Peracetyl-Fucose
2F-Peracetyl-Fucose is a cell-permeable fluorinated fucose derivative that acts as an inhibitor of fucosyltransferases following its uptake and metabolic transformation into a GDP-fucose mimetic.
MilliporeSigma™ Calbiochem™ 5-Fluoro-2'-deoxyuridine
Experimental anticancer agent shown to have activity against a variety of malignant neoplasms, including mouse mammary tumors and colorectal carcinomas.
MilliporeSigma™ Calbiochem™ ω-Conotoxin GVIA, Conus geographus
A neurotoxin that acts as an antagonist of voltage-activated N-type Ca2+ channels and of neurotransmitter release at neuronal synapses.
MilliporeSigma™ Calbiochem™ ET-18-OCH3
A cell-permeable and reversible cytotoxic agent that shows selective cytocidal activity against neoplastic cells and virally transformed cells.
MilliporeSigma™ Calbiochem™ Etoposide
Etoposide, CAS 33419-42-0, is cell-permeable inhibitor of topoisomerase II inhibitor (IC50 = 59.2μM). Displays anti-tumor activity.
MilliporeSigma™ Calbiochem™ Fatostatin
A cell-permeable diarylthiazole compound that prevents the cellular activation of the SREBP-1/2 precursors to the active nuclear forms by blocking SREBPs-SCAP ER to Golgi translocation.
MilliporeSigma™ Calbiochem™ Foxo1 Inhibitor, AS1842856
Foxo1 Inhibitor, AS1842856, is a cell-permeable inhibitor that blocks the transcription activity of Foxo1 (IC50 = 33 nM). Directly binds to the active Foxo1, but not the Ser256-phosphorylated form.
MilliporeSigma™ Calbiochem™ Guanosine 3',5'-cyclic Monophosphorothioate, β-Phenyl-1,N2-etheno-8-bromo-, Rp-Isomer, Sodium Salt
A metabolically-stable, competitive inhibitor of protein kinase G types 1α and 1β (Ki = 30 nM).
MilliporeSigma™ Calbiochem™ Pristimerin
A cell-permeable plant dienone-phenolic triterpenoid, naturally isolated from tripterygium wilfordii.
MilliporeSigma™ Calbiochem™ Cathepsin L Inhibitor II
The Cathepsin L Inhibitor II controls the biological activity of Cathepsin L. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ NFAT Inhibitor, MCV1
The NFAT Inhibitor, MCV1 controls the biological activity of NFAT.
MilliporeSigma™ Calbiochem™ InSolution™ ATM Kinase Inhibitor
The InSolution™ ATM Kinase Inhibitor controls the biological activity of ATM Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Fluvastatin, Sodium Salt
A synthetic HMG-CoA reductase inhibitor (IC50 = 40-100 nM for human liver microsomes) that acts as an anti-hypercholesterolemic agent.
MilliporeSigma™ Calbiochem™ W-13, Hydrochloride
A cell-permeable and reversible calmodulin antagonist that inhibits myosin light chain kinase (IC50 = 58 μM) and Ca2+-calmodulin-dependent phosphodiesterase (IC50 = 68 μM).