Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ Foxo1 Inhibitor, AS1842856
Foxo1 Inhibitor, AS1842856, is a cell-permeable inhibitor that blocks the transcription activity of Foxo1 (IC50 = 33 nM). Directly binds to the active Foxo1, but not the Ser256-phosphorylated form.
MilliporeSigma™ Calbiochem™ CNQX
A potent and competitive antagonist for AMPA/kainate receptors (Ki
MilliporeSigma™ Calbiochem™ GTS-21 Dihydrochloride (DMBX-A)
A partial agonist selective for α7 nAChRs (EC50 = 10
MilliporeSigma™ Calbiochem™ Glucagon Receptor Antagonist II
The Glucagon Receptor Antagonist II, also referenced under CAS 191034-25-0, controls the biological activity of Glucagon Receptor.
MilliporeSigma™ Calbiochem™ ERK Inhibitor
The ERK Inhibitor, also referenced under CAS 1049738-54-6, controls the biological activity of ERK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Emodin
A cell-permeable, reversible, substrate competitive and potent p56lck tyrosine kinase inhibitor (IC50 = 18.5 μM).
MilliporeSigma™ Calbiochem™ Elastase Substrate I, Colorimetric
A specific chromogenic substrate for human neutrophil elastase.
MilliporeSigma™ Calbiochem™ eIF4E/eIF4G Interaction Inhibitor, 4EGI-1
eIF4E/eIF4G Interaction Inhibitor, 4EGI-1, CAS 315706-13-9, is a cell-permeable compound that reversibly binds eIF4E (KD = 25 μM) and disrupts eIF4E/eIF4G complex formation.
MilliporeSigma™ Calbiochem™ Eeyarestatin I
A cell-permeable oxo-imidazolidinyl-hydroxyurea that localizes to ER, where it interacts with AAA ATPase p97 via its nitrofuran-containing moiety, without exhibiting affinity toward Hsp70 / ATPase NSF
MilliporeSigma™ Calbiochem™ ET-18-OCH3
A cell-permeable and reversible cytotoxic agent that shows selective cytocidal activity against neoplastic cells and virally transformed cells.
MilliporeSigma™ Calbiochem™ Etoposide
Etoposide, CAS 33419-42-0, is cell-permeable inhibitor of topoisomerase II inhibitor (IC50 = 59.2μM). Displays anti-tumor activity.
MilliporeSigma™ Calbiochem™ N-Ethylmaleimide
Sulfhydryl alkylating reagent that inhibits H+-ATPase and suppresses the short circuit current (IC50 = 22 μM) in pancreatic duct cells.
MilliporeSigma™ Calbiochem™ InSolution™ U0126
A potent and specific inhibitor of MEK1 and MEK2 .
MilliporeSigma™ Calbiochem™ Ibotenic Acid
A highly potent agonist of NMDA and mGlu receptors.
MilliporeSigma™ Calbiochem™ TACE Substrate IV, Fluorogenic
An internally-quenched fluorogenic decapeptide substrate that is useful for continuous monitoring of TACE activity and high-throughput screening of TACE inhibitors (kcat =