Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ AGE Inhibitor, LR-90
A cell-permeable blocker of advanced glycation end product formation.
MilliporeSigma™ Calbiochem™ PKM2 Activator IV, TEPP-46
A cell-permeable, potent, allosteric activator of PKM2 (AC50 = 92 nM).
MilliporeSigma™ Calbiochem™ γ-Secretase Inhibitor XX
This γ-secretase inhibitor, CAS 209984-56-5, is a cell-permeable dibenzazepine compound that lowers both brain and plasma Aβ40 levels by ≈72% in Tg2576 mutant APP transgenic mouse model.
MilliporeSigma™ Calbiochem™ Sodium Orthovanadate
A broad spectrum potent inhibitor of protein tyrosine phosphatases.
MilliporeSigma™ Calbiochem™ Sodium Stibogluconate
Sodium Stibogluconate, CAS 16037-91-5, is a pentavalent antimony compound that irreversibly inhibits protein tyrosine phosphatase activity, including SHP-1, by forming a stable complex.
MilliporeSigma™ Calbiochem™ SU1498
A potent, reversible, ATP-competitive and selective inhibitor of Flk-1 kinase (IC50 = 700 nM), a vascular endothelial growth factor (VEGF) receptor kinase.
MilliporeSigma™ Calbiochem™ STAT5 Inhibitor III, Pimozide
The STAT5 Inhibitor III, Pimozide, also referenced under CAS 2062-78-4, controls the biological activity of STAT5.
MilliporeSigma™ Calbiochem™ Syk Inhibitor IV, BAY 61-3606
The Syk Inhibitor IV, BAY 61-3606, also referenced under CAS 732938-37-8, controls the biological activity of Syk.
MilliporeSigma™ Calbiochem™ MEK Inhibitor I
The MEK Inhibitor I, also referenced under CAS 297744-42-4, controls the biological activity of MEK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Chk2 Inhibitor, PV1019
The Chk2 Inhibitor, PV1019 controls the biological activity of Chk2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ 2-Chloro-2'-deoxyadenosine
A deoxyadenosine analog that displays strong antileukemic and immunosuppressive activity.
MilliporeSigma™ Calbiochem™ Chk2 Inhibitor
The Chk2 Inhibitor, also referenced under CAS 724708-21-8, controls the biological activity of Chk2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.