Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ MAGL Inhibitor III, JZL184
The MAGL Inhibitor III, JZL184, also referenced under CAS 1101854-58-3, controls the biological activity of MAGL.
MilliporeSigma™ Calbiochem™ MG-132
A cell-permeable, potent, reversible proteasome inhibitor (Ki = 4 nM).
MilliporeSigma™ Calbiochem™ Myosin Light Chain Kinase Inhibitor Peptide 18
The Myosin Light Chain Kinase Inhibitor Peptide 18 controls the biological activity of Myosin Light Chain Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Mitochondrial Division Inhibitor, mdivi-1
The Mitochondrial Division Inhibitor, mdivi-1, also referenced under CAS 338967-87-6, controls the biological activity of yeast Dnm1 and mammalian Drp1.
MilliporeSigma™ Calbiochem™ InSolution™ Microcystin-LR, Microcystis aeruginosa
Cyclic heptapeptide toxin isolated from the freshwater cyanobacteria, Microcystis aeruginosa
MilliporeSigma™ Calbiochem™ Nicotinamide Phosphoribosyltransferase Inhibitor, FK866
The Nicotinamide Phosphoribosyltransferase Inhibitor, FK866, also referenced under CAS 658084-64-1, controls the biological activity of Nicotinamide Phosphoribosyltransferase. This small molecule/inhibitor is primarily used for Neuroscience applications.
MilliporeSigma™ Calbiochem™ Myriocin, Mycelia sterilia
A potent immunosuppressant.
MilliporeSigma™ Calbiochem™ Nifuroxazide
A cell-permeable and orally available nitrofuran-based antidiarrheal agent that effectively suppresses the activation of cellular STAT1/3/5 transcription activity.
MilliporeSigma™ Calbiochem™ 4-Hydroxynonenal
4-Hydroxynonenal, CAS 75899-68-2, is a major aldehyde product formed by peroxidation of ω-6-unsaturated fatty acids that is regarded as a specific marker of lipid peroxidation.
MilliporeSigma™ Calbiochem™ Honokiol
A biphenyl neolignan and an active principle of Magnolia extract that displays anti-angiogenic, anti-tumor and anxiolytic properties.
MilliporeSigma™ Calbiochem™ CL-82198
A selective inhibitor of MMP-13 (IC50 = 10 μM).
MilliporeSigma™ Calbiochem™ Topoisomerase II Inhibitor, BNS-22
The Topoisomerase II Inhibitor, BNS-22 controls the biological activity of Topoisomerase. This small molecule/inhibitor is primarily used for Cell Structure applications.
MilliporeSigma™ Calbiochem™ KN-93
A cell-permeable, reversible and competitive inhibitor of rat brain CaM kinase II (Ki = 370 nM).
MilliporeSigma™ Calbiochem™ Ketohexokinase Inhibitor
An orally bioavailable pyrimidinopyrimidine compound that acts as a potent, reversible and ATP-competitive inhibitor of human hepatic KHK activity (KHK-C isoform; IC50 = 12nM in a transcreener ADP assay) and efficiently blocks fructose-1-phosphate secretion (IC50 ≤ 400nM in HepG2
MilliporeSigma™ Calbiochem™ Nedd4/Rsp5 Signaling Inducer, NAB2
A cell-permeable compound that protects against alpha-synuclein toxicity.