Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ Rho Inhibitor, Rhosin
Rho Inhibitor, Rhosin, CAS 1173671-63-0, is a cell-permeable compound that directly targets Rho GEF binding domain (Kd = 354nM for RhoA), thereby prevents Rho from interacting with its GEFs.
MilliporeSigma™ Calbiochem™ Ketanserin Tartrate
A selective 5-HT2A serotonin receptor antagonist with weak adrenergic receptor blocking propert
MilliporeSigma™ Calbiochem™ eEF-2 Kinase Inhibitor, NH125
The eEF-2 Kinase Inhibitor, NH125, also referenced under CAS 278603-08-0, controls the biological activity of eEF-2 Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Carbonic Anhydrase IX/XII Inhibitor
The Carbonic Anhydrase IX/XII Inhibitor controls the biological activity of Carbonic Anhydrase IX/XII. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ Caspase-3 Inhibitor II
The Caspase-3 Inhibitor II, also referenced under CAS 210344-95-9, controls the biological activity of Caspase-3. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ PARP Inhibitor I, 3-ABA
The PARP Inhibitor I, 3-ABA, also referenced under CAS 3544-24-9, controls the biological activity of PARP. This small molecule/inhibitor is primarily used for Cell Structure applications.
MilliporeSigma™ Calbiochem™ IRAK4 Inhibitor, Compound 26
A cell permeable indolo[2,3-c]quinoline derivatived compound that acts as a selective and highly potent inhibitor of interleukin-1 receptor associated kinase (IRAK4; IC50 = 94
MilliporeSigma™ Calbiochem™ ProRS Inhibitor, Halofuginone
A cell-permeable racemic mixture of Halofuginone that inhibits of prolyl-tRNA synthetase.
MilliporeSigma™ Calbiochem™ NBD-Binding Peptide II, Cell Permeable, CTP-NBD
A cell-permeable cytoplasmic transduction peptide (CTP; YGRRARRRARR) fused to the NEMO binding domain peptide (NBD; TALDWSWLQTE) that acts as a potent inhibitor of TNFα-stimulated NF-κB activity (IC50∽ 50μM in HCT116 cells).
MilliporeSigma™ Calbiochem™ Calpastatin Peptide
A 27-amino acid, cell-permeable peptide encoded by exon 1B of human calpastatin that acts as a potent inhibitor of calpain I and calpain II (IC50 = 20 nM for purified rabbit calpain II).
MilliporeSigma™ Calbiochem™ InSolution™ Akt Inhibitor V, Triciribine
The InSolution™ Akt Inhibitor V, Triciribine, also referenced under CAS 35943-35-2, controls the biological activity of Akt. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Ursolic Acid
A cell-permeable plant-derived pentacyclic triterpene acid that displays anti-inflammatory, immunomodulatory, and antitumor activities.
MilliporeSigma™ Calbiochem™ Cathepsin G Substrate IV, Fluorogenic
An internally quenched fluorogenic peptide substrate (Mca/Anb as fluorophore/quencher) that is preferentially cleaved by cathepsin G between Gnf and Ser with high efficiency and selectivity.
MilliporeSigma™ Calbiochem™ Piperlongumine
A cell-permeable, orally bioavailable natural product isolated from the plant species, Piper longum L, which selectively induces cell death in cancer cells that express both wild-type and mutant p53.
MilliporeSigma™ Calbiochem™ TRPC3 Channel Inhibitor III, Pyr10
A cell-permeable pyrazole derivative that acts as a selective blocker of the transient receptor potential cation channel TRPC3-medated ROCE (receptor-operated Ca2+ entry) and inhibits Carbachol- (