Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ Cyclo(Arg-Gly-Asp-D-Phe-Val)
Potent inhibitor of cell adhesion.
MilliporeSigma™ Calbiochem™ D-erythro-Sphingosine, N,N-Dimethyl-
A cell-permeable and reversible inhibitor of protein kinase C (PKC; IC50 = 12 μM) and stimulates Src kinase activity.
MilliporeSigma™ Calbiochem™ Eeyarestatin I
A cell-permeable oxo-imidazolidinyl-hydroxyurea that localizes to ER, where it interacts with AAA ATPase p97 via its nitrofuran-containing moiety, without exhibiting affinity toward Hsp70 / ATPase NSF
MilliporeSigma™ Calbiochem™ GTS-21 Dihydrochloride (DMBX-A)
A partial agonist selective for α7 nAChRs (EC50 = 10
MilliporeSigma™ Calbiochem™ Aurora Kinase Inhibitor VI, ZM447439
The Aurora Kinase Inhibitor VI, ZM447439, also referenced under CAS 331771-20-1, controls the biological activity of Aurora Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Golgicide A
A cell-permeable quinoline compound that selectively targets ArfGEF GBF1, but not BIG1/2, and attenuates GBF1-mediated cellular vesicle traffickings in a reversible manner.
MilliporeSigma™ Calbiochem™ Caspase Inhibitor VI
Z-VAD-FMK, CAS 161401-82-7, is an irreversible pan caspase inhibitor. Does not require pretreatment with esterase for in vitro studies.
MilliporeSigma™ Calbiochem™ JNK Inhibitor III, Cell-Permeable
The JNK Inhibitor III, Cell-Permeable controls the biological activity of JNK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ GGTI-2147
A cell-permeable non-thiol peptidomimetic that acts as a potent and selective inhibitor of geranylgeranyltransferase I (GGTase I).
MilliporeSigma™ Calbiochem™ Tau Aggregation Inhibitor, ATPZ, Cpd16
A water soluble (32uM in water) BBB-permeable ATPZ (aminothienopyridazine) tau aggregation inhibitor
MilliporeSigma™ Calbiochem™ InSolution™ MG-132 in EtOH, ≥95% by HPLC
Potent, reversible, and cell-permeable proteasome inhibitor. Reduces the degradation of ubiquitin-conjugated proteins in mammalian cells and permeable stains of yeast by the 26S complex.
MilliporeSigma™ Calbiochem™ Bisindolylmaleimide IV
A potent, cell permeable, and selective inhibitor of protein kinase C (IC50 = 87 nM).
MilliporeSigma™ Calbiochem™ Collagenase Inhibitor I
The Collagenase Inhibitor I controls the biological activity of Collagenase. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ RHC-80267
Selective inhibitor of DAG lipase activity in canine platelets (IC50 = 4 nM) and in a variety of mammalian cells.
MilliporeSigma™ Calbiochem™ Akt Inhibitor XIII, Isozyme-Selective, Akti2-1/2
The Akt Inhibitor XIII, Isozyme-Selective, Akti2-1/2 controls the biological activity of Akt. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.