Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ PKCζ Pseudosubstrate Inhibitor, Myristoylated
PKCζ Pseudosubstrate Inhibitor is a myristoylated, cell-permeable, reversible, substrate competitive inhibitor of protein kinase Cζ.
MilliporeSigma™ Calbiochem™ AICA-Riboside
AICA-Riboside, CAS 2627-69-2, is a cell-permeable nucleoside compound whose phosphorylated metabolite activates AMPK and acts as a regulator of de novo purine synthesis.
MilliporeSigma™ Calbiochem™ Ilimaquinone
A cell-permeable marine sponge metabolite with anti-microbial, anti-HIV, anti-inflammatory, and anti-mitotic properties.
MilliporeSigma™ Calbiochem™ PI 3-K/mTOR Inhibitor III, PKI-179
The PI 3-K/mTOR Inhibitor III, PKI-179, also referenced under CAS 1197160-28-3, controls the biological activity of PI 3-K/mTOR. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Apoptosis Activator VII, Apoptozole
The Apoptosis Activator VII, Apoptozole, also referenced under CAS 1054543-47-3, modulates Apoptosis. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ Smad3 Inhibitor, SIS3
Smad3 Inhibitor, SIS3, CAS 1009104-85-1, is a cell-permeable, selective inhibitor of TGF-β1-dependent Smad3 phosphorylation and Smad3-mediated signaling. Does not affect Smad2, MAPK, ERK, or PI3-K.
MilliporeSigma™ Calbiochem™ RORγt Inverse Agonist II, GSK805
A cell-permeable, potent, non-toxic, inverse agonist of RORγt. Directly and reversibly interacts with the ligand binding domain of RORγt to block its transcriptional effects.
MilliporeSigma™ Calbiochem™ MMP-2/MMP-9 Substrate I, Fluorogenic
A fluorogenic substrate for both the 72 kDa human fibroblast gelatinase (HFG; MMP-2) and the 92 kDa human neutrophil gelatinase (HNG; MMP-9).
MilliporeSigma™ Calbiochem™ MMP-13 Substrate, Fluorogenic
A quenched fluorescence substrate for MMP-13 (collagenase-3; kcat/Km = 1.09 x 106 M-1 s-1).
MilliporeSigma™ Calbiochem™ Glucose Transporter Inhibitor IV, WZB117
The Glucose Transporter Inhibitor IV, WZB117 controls the biological activity of Glucose Transporter.
MilliporeSigma™ Calbiochem™ Licochalcone-A, Synthetic
An estrogenic flavonoid with anti-tumor and antiparasitic properties.
MilliporeSigma™ Calbiochem™ NMDA Antagonist XI, N1-dansyl-spermine
An N-sulfonyl-polyamine that acts as a potent and more specific antagonist of NMDA receptors expressed in Xenopus oocytes (IC50 = 310, 340nM in NR1/NR2A and NR1/NR2B, respective
MilliporeSigma™ Calbiochem™ Aromatase Inhibitor I
The Aromatase Inhibitor I, also referenced under CAS 331684-05-0, controls the biological activity of Aromatase.
MilliporeSigma™ Calbiochem™ Adenosine A1 Receptor Antagonist I, DPCPX
A blood-brain barrier permeable xanthine derivative that acts as a highly selective antagonist of Adenosine A1 receptor (A1R; Ki
MilliporeSigma™ Calbiochem™ RIPK3 Inhibitor, GSK'872
A cell-permeable, selective inhibitor of RIP3-selective kinase with >1,000-fold selectivity over a vast majority of more than 300 other kinases.