Other Controls and Reagents
Avanti Polar Lipids 7-dehydrocholesterol | 434-16-2 | 5mg
7-dehydrocholesterol | Purity: 95% | Mol Wt: 384.644 | 434-16-2 | 5mg
Medchemexpress LLC Monophosphoryl lipid A (Glucopyranosyl lipid A) | 1246298-63-4 | 99.9% | 1 MG
Monophosphoryl lipid A (Glucopyranosyl lipid A) is a toll-like receptor 4 agonist derived from the cell wall of nonpathogenic Salmonella. It is used for research on immunization and vaccines.
- Induces NF-κB activation.
- Modulates TLR2.
- Induces IL-12 production by human dendritic cells.
- Up-regulates dendritic cell surface markers.
- Enhances T cell responses.
- Increases calcium mobilization of activated T cells.
- Activates APC and enhances the generation of both Th1- and Th2-specific immune response in mice.
Medchemexpress LLC Dspe-peg2000-pdp | 474922-24-2 | >90.0% | C140H273N4O55PS2 | 50 MG
DSPE-PEG2000-PDP is a phospholipid PEG conjugate that can be used in drug delivery applications.
- Used in drug delivery applications.
Apexbio Technology LLC DMG-PEG2000-N3 100mg
DMG-PEG2000-N3 is a PEGylated lipid derivative utilized for the functionalization of lipid-based drug delivery systems It consists of 1 2-dimyristoyl-sn-glycerol (DMG) polyethylene glycol (PEG 2000 Da) and a terminal azide group (N3) The azide functional group enables selective conjugation via copper-catalyzed azide-alkyne cycloaddition (CuAAC or click chemistry) allowing controlled attachment of biomolecules small-molecule drugs fluorescent probes or targeting ligands onto lipid bilayers DMG-PEG2000-N3 is widely applied in the development of liposomal or nanoparticle formulations for targeted drug delivery and imaging in biomedical research
Medchemexpress LLC DLin-KC2-DMA | 1190197-97-7 | ≥98.0% | 642.09 | 25 MG
DLin-KC2-DMA is an ionizable cationic lipid (pKa≈6) that is virtually non-toxic to antigen presenting cells (APCs). It produces significant siRNA-mediated gene silencing of GAPDH when bound to lipid nanoparticles (LNP). DLin-KC2-DMA can be used in siRNA delivery studies.
- Ionizable cationic lipid (pKa≈6).
- Virtually non-toxic to antigen presenting cells (APCs).
- Produces significant siRNA-mediated gene silencing of GAPDH when bound to lipid nanoparticles (LNP).
- Can be used in siRNA delivery studies.
- High uptake into macrophages and dendritic cells.
- Efficiently promotes release of encapsulated siRNA into the cytosol following uptake via the endocytotic pathway.
- Displays almost no toxicity in primary APCs.
- Effective in silencing target genes in APCs in vivo (5 mg/kg; i.v.; single).
![Medchemexpress LLC 3-[2,2-bis[(9Z,12Z)-octadeca-9,12-dienyl]-1,3-dioxolan-4-yl]-N,N-dimethylpropan-1-amine | 1217306-46-1 | >98.0% | C44H81NO2 | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000261464.png-250.jpg)
Medchemexpress LLC 3-[2,2-bis[(9Z,12Z)-octadeca-9,12-dienyl]-1,3-dioxolan-4-yl]-N,N-dimethylpropan-1-amine | 1217306-46-1 | >98.0% | C44H81NO2 | 10MG
A synthetic cationic lipid used in the formulation of nucleic acid-lipid particles (LNPs) for research delivery of RNA and DNA. It promotes encapsulation and cellular uptake of nucleic acids when combined with helper lipids and is supplied for laboratory research use only.
- Cationic lipid for formulation of nucleic acid-lipid particles.
- Facilitates encapsulation and delivery of RNA and DNA.
- High purity suitable for research applications.
- Powder form, soluble in DMSO for preparation of stock solutions.
- Recommended storage at -20°C to maintain stability.
eMolecules BP Lipid 146 | Broadpharm |682.128 | C42H83NO5 | 0.000 | CCCCCCCCC(CCCCCCCC)OC(=O)CCCCCCCN(CCCO)CCCCCCC(=O)OCCCCCCC | 50mg | 672542562
BP Lipid 146 | Broadpharm |682.128 | C42H83NO5 | 0.000 | CCCCCCCCC(CCCCCCCC)OC(=O)CCCCCCCN(CCCO)CCCCCCC(=O)OCCCCCCC | 50mg | 672542562
Cayman Chemical DLIn-MC2-DMA 1mg
An ionizable cationic lipid; has been used in the formation of LNPs; LNPs containing DLin-MC2-DMA and encapsulating siRNA targeting mRNA encoding FVII reduce hepatic levels of FVII in mice (ED50 = 0.6 mg/kg)