Substrates
Medchemexpress LLC Nicotinamide 1,N6-ethenoadenine dinucleotide | 38806-38-1 | MFCD00063546 | 99.0% | C23H27N7O14P2 | 10MG
Nicotinamide 1,N6-ethenoadenine dinucleotide (ε-NAD) is a fluorescent β-NAD analog used as a probe in biochemical and enzymology research. It serves as a fluorescent substrate for studies of nucleotide-protein interactions and ADP-ribosylation reactions. The compound is supplied as a white to off-white solid with high purity and is provided in small research pack sizes with supporting documentation.
Cayman Chemical Cdk5 Substrate trifluoroacet
A synthetic peptide (PKTPKKAKKL) corresponding to a sequence of histone H1; phosphorylated by Cdk5 with a Km value of 5 µM
![Research Products International Corp X-a-Gal [5-Bromo-4-Chloro-3-indolyl-a-D-galactoside], 1 Gram](https://assets.fishersci.com/TFS-Assets/CCG/product-images/VN00006095-B71900-1.014.JPG-250.jpg)
Research Products International Corp X-a-Gal [5-Bromo-4-Chloro-3-indolyl-a-D-galactoside], 1 Gram
Chromogenic substrate for detection of a-galactosidase activity in yeast Saccharomyces cerevisiae. Used in yeast Two-Hybrid System to detect protein-protein interactions within random libraries. The enzyme a-galactosidase enabels yeast to use disaccharide melibose as a carbon source during growth or fermentation. Secretion of this enzyme in response to activation of the GAL4 gene hydrolizes X-a-GAL and causes yeast colonies to develop a blue color. This reporter system allows immediate visible results on selection plates and eliminates necessity of a second screen filter life assay.
Ubpbio K48-linked tri-Ubiquitin (human), enzymatically synthesized
Ub chains are formed by conjugating the C-terminal glycine residue of Ub onto any of seven internal lysine residues or the amino group of the previous Ub. Ub chains are classified by the lysine residue used to link Ubs; different Ub chain topologies can result in different signals. For instance, Ub chains linked through lysine 6, 11, 27, 29, 33 and 48 are capable of targeting proteins for proteasomal degradation; in contrast, Ub chains linked through lysine 63 or the N-terminal amino group (linear Ub chains) often play important nonproteolytic functions including regulation of kinase activation and protein translation. All Ub chain products are produced by using of human wild type Ub reacting with specific E2s.
Gold Biotechnology Inc Lysozyme, Egg White 5 g
Lysozyme is an enzyme capable of breaking down the bacterial cell wall, and is typically used to enhance protein extractions or nucleic acid extractions. It works by hydrolyzing the 1,4-β-linkages located between the N-acetylmuramic acid and the N-acetyl-D-glucosamine residues in peptidoglycan.
![Research Products International Corp NPG [4-Nitrophenyl-B-D-glucuronide], 1 Gram](https://assets.fishersci.com/TFS-Assets/CCG/product-images/VN00006095-N12030-1.0.JPG-250.jpg)
Research Products International Corp NPG [4-Nitrophenyl-B-D-glucuronide], 1 Gram
Spectrophotometric substrate for detection of B-D-Glucuronidase.
Biotium HER-2 / CD340(ERB2/776), CF740 conjugate, 0.1mg/mL
This MAb is specific to c-erbB-2/HER-2 and shows minimal cross-reaction with other members of the family. C-erbB-2/HER-2 is a member of the EGFR family. Receptors of this family are located on the plasma membrane and consist of an extracellular ligand-binding domain that is connected to a large intracellular domain by a single transmembrane sequence. c-erbB-2/HER-2 protein is over-expressed in a variety of carcinomas especially those of breast and ovary.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Medchemexpress LLC Ac-YEVD-AMC | 1631716-11-4 | 99.6% | 723.73 | 5 MG
Ac-YEVD-AMC is a fluorescent substrate of caspase-1/11 that releases amino-4-methylcoumarin (AMC) for fluorescence detection when treated with cell lysate. This product is for research use only.
- Fluorescent substrate of caspase-1/11
- Releases amino-4-methylcoumarin (AMC) for fluorescence detection
- For research use only
Medchemexpress LLC Ac-IETD-AFC | 211990-57-7 | 99.3% | 729.65 | 10 MG
Ac-IETD-AFC is a fluorogenic substrate for caspases-8, -3, and -10, as well as granzyme B. This product is intended for research use only and is not sold to patients.
- Fluorogenic substrate for caspase-8, caspase-3, caspase-10, and granzyme B
- Suitable for enzyme labeling and fluorescence studies
- Used in apoptosis and caspase research
- Excitation wavelength less than 380 nm
- Emission wavelength 496-570 nm (green)
Medchemexpress LLC Z-Gly-Gly-Arg-AMC acetate | 2070009-61-7 | 99.84% | 639.66 | 50 MG
Z-Gly-Gly-Arg-AMC acetate is a thrombin-specific fluorogenic substrate primarily used for testing thrombin generation in both platelet-rich plasma (PRP) and platelet-poor plasma (PPP). This compound, characterized by excitation/emission wavelengths of 390/480 nm, is provided as a solid, typically white to off-white, and is strictly for research applications.
- Thrombin-specific fluorogenic substrate
- Suitable for thrombin generation assays in PRP and PPP
- Exhibits excitation at 390 nm and emission at 480 nm
- Supplied as a white to off-white solid
- Intended for research use only
Medchemexpress LLC HER2/CD340 Human H 10ug
The HER2/CD340 protein is a dynamic tyrosine kinase that is essential in the neuregulin receptor complex and regulates microtubule dynamics Upon activation it triggers the MEMO1-RHOA-DIAPH1 pathway inhibits GSK3B and promotes the association of APC and CLASP2 on the cell membrane to achieve microtubule stabilization HER2/CD340 Protein Human (HEK293) is the recombinant human-derived HER2/CD340 protein expressed by HEK293 with tag free
Sino Biological Peptide Substrates: IGF1Rtide
The 14 amino acids of IGF1Rtide peptide sequence (KKKSPGEYVNIEFG) is derived from human IRS-1 protein residues 891-902.
Enzo Life Sciences Ac-YVAD-AFC (10mg)
Substrate for caspase-1 and -4. Fluorogenic substrate for caspase-1 and -4. Alternative name: Caspase 1 substrate (fluorogenic), Caspase 4 substrate (fluorogenic). Formula: C33H36F3N5O10. MW: 719.7. Purity: ≥97% (HPLC). Appearance: White to off-white powder. Solubility: Soluble in DMSO. Long Term Storage: -20°C. Use/Stability: Solid product is stable for 1 year in desiccator when stored at room temperature. Stock solutions are stable for 6 – 8 months when stored at –20°C. Keep sealed after removing from the freezer until its temperature equilibrates with room temperature. Handling: Keep cool and dry.
CPC Scientific Ac-Ile-Glu-Thr-Asp-AFC 1MG
Specific substrate for caspase-8.SEQUENCE: Ac-Ile-Glu-Thr-Asp-AFCONE-LETTER SEQUENCE: Ac-IETD-AFCMOLECULAR FORMULA: C31H38F3N5O12MOLECULAR WEIGHT: 729.7STORAGE CONDITIONS: -20 5 CCAS REGISTRY NUMBER: [211990-57-7]SYNONYMS: N-Acetyl-Ile-Glu-Thr-Asp-7-amino-4-TrifluoromethylcoumarinRESEARCH AREA: ApoptosisREFERENCES:Reszka, P., Schulz, R., Methling, K., et al. ChemMedChem 5(1), 103-117 (2010).SKU(s): CASP-095A, CASP-095B
Abcam 4-Trifluoromethylumbelliferyl oleate, 10MG
MW 494.6 Da. Fluorescent lipase substrate. Releases highly fluorescent 4-trifluoromethylumbelliferone upon hydrolysis. 4-trifluoromethylumbelliferone is insensitive to pH making it suitable for use in food analysis.
The product is subject to the following: Abcam Restricted Use Statement