Substrates
Cayman Chemical SucAAPAbupNAtrIfluoroace 1mg
A substrate for pancreatic elastase; cleaved by elastase to release p-NA, which can be quantified by colorimetric detection at 405 nm as a measure of enzyme activity
ABclonal Technology Phospho-c-Abl-Y412 Rabbit pAb
This gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes, including cell division, adhesion, differentiation, and response to stress. The activity of the protein is negatively regulated by its SH3 domain, whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA-binding activity that is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function. This gene has been found fused to a variety of translocation partner genes in various leukemias, most notably the t(9,22) translocation that results in a fusion with the 5 end of the breakpoint cluster region gene (BCR, MIM151410). Alternative splicing of this gene results in two transcript variants, which contain alternative first exons that are spliced to the remaining common exons.
Cayman Chemical Ac-QPKK Ac-AMC 10mg
A fluorogenic substrate for SIRT1, SIRT2, and SIRT3; AMC is released upon enzymatic cleavage by SIRT1, SIRT2, or SIRT3 and its fluorescence can be used to quantify SIRT1, SIRT2, and SIRT3 activity; ex/em = 340-360/440-460 nm, respectively
Cayman Chemical Pntothenate-AMC 1mg
A fluorogenic substrate for vanin-1; AMC is released upon enzymatic cleavage by vanin-1 and its fluorescence can be used to quantify vanin-1 activity; ex/em = 340-360/440-460 nm, respectively
Cayman Chemical Ac-DNLD-AMC 1mg
A fluorogenic caspase-3 substrate; upon enzymatic cleavage by caspase-3, AMC is released and its fluorescence can be used to quantify caspase-3 activity; AMC ex/em = 340-360/440-460 nm, respectively
ABclonal Technology Phospho-c-Abl-Y412 Rabbit pAb
This gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes, including cell division, adhesion, differentiation, and response to stress. The activity of the protein is negatively regulated by its SH3 domain, whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA-binding activity that is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function. This gene has been found fused to a variety of translocation partner genes in various leukemias, most notably the t(9,22) translocation that results in a fusion with the 5 end of the breakpoint cluster region gene (BCR, MIM151410). Alternative splicing of this gene results in two transcript variants, which contain alternative first exons that are spliced to the remaining common exons.
Medchemexpress LLC Receptor tyrosine-protein kinase ErbB-2 (HER2/CD340), rhesus macaque, recombinant, His-tagged | >95.0% | 50 UG
Recombinant HER2/CD340 protein from rhesus macaque (extracellular residues Q24-T652) is produced in HEK293 cells with a C-terminal His tag and supplied lyophilized for use in antibody characterization, ligand binding assays, and signaling studies.
- Mammalian expression preserves native folding and glycosylation.
- C-terminal His tag enables affinity purification and detection.
- Purity greater than 95% as determined by reducing SDS-PAGE.
- Lyophilized from PBS, pH 7.4, for improved stability and storage.
- Available in multiple sizes, including a 50 μg vial.
Medchemexpress LLC Arg-Arg-AMC acetate | 487.56 | 1 MG
Arg-Arg-AMC acetate is the acetate salt form of Arg-Arg-AMC. It functions as a fluorescent substrate for cathepsin B and is utilized in cathepsin B activity assays.
- Fluorescent substrate for cathepsin B
- Used in cathepsin B activity assays
- Acetate salt form
Medchemexpress LLC NQO1 substrate | 50MG
NQO1 substrate acts as an efficient NQO1 substrate and may be a new option for the treatment of NQO1-overexpresssing drug-resistant NSCLC[1]
Medchemexpress LLC 6'-Amino-D-luciferin | 161055-47-6 | 98.5% | 25 MG
6'-Amino-D-luciferin is a derivative of D-luciferin with an amino group replacing the 6-hydroxyl group. It serves as a natural substrate of luciferase (Luc) and is utilized for IVIS imaging in various cell and animal experimental settings.
- Derivative of D-luciferin
- Features an amino group replacing the 6-hydroxyl group
- Natural substrate for luciferase (Luc)
- Applicable for IVIS imaging in cell and animal experiments
- Red-shifts bioluminescence spectrum of green-yellow emitting luciferase
- Blue-shifts bioluminescence spectrum of red-emitting luciferase
- Used to analyze interaction of binding mutant active sites (λmax=588 nm)
- Capable of detecting apoptotic signals in tumor models
Sino Biological SwiftFluo TR-FRET TKs substrate - biotin 250 nmol
SwiftFluo TR-FRET TKs substrate - biotin is designed for measuring the Tyrosine kinase (TKs) activity with SwiftFluor™ TR-FRET TKs kinase kit (Cat. # SFKA001).
Medchemexpress LLC Z-leu-leu-glu-AMC | 348086-66-8 | MFCD01074989 | 99.5% | 664.75 | C35H44N4O9 | 10MG
Z-Leu-Leu-Glu-AMC is a fluorogenic tripeptide substrate used to quantify the post-acidic (peptidylglutamyl) hydrolyzing activity of the 20S proteasome. Proteolytic cleavage releases the 7-amino-4-methylcoumarin (AMC) fluorophore, enabling sensitive fluorescence-based assays for biochemical research and enzyme activity screening.
- Fluorogenic substrate that releases AMC upon proteolysis.
- Suitable for measuring peptidylglutamyl-peptide hydrolyzing (PGPH/caspase-like) proteasome activity.
- High reported purity for reliable assay results.
- Available as lyophilized solid and as solution in DMSO for easy reconstitution.
- Characterized by molecular weight 664.75 and formula C35H44N4O9.
Revvity Health Sciences Inc LANCE Ultra IκBα Ulight Peptide Substrate, 0.5 nmole
LANCE Ultra IκBα Ulight Peptide Substrate, 0.5 nmole
Cell Signaling Technology PathScanR Phospho-p53 Ser15 Sandwich ELISA Kit 50 Kit
PathScanR Phospho-p53 Ser15 Sandwich ELISA Kit 50 Kit
![eMolecules 115144-35-9 | D-Luciferin (potassium) | Medchem Express | MFCD00044928 | 318.410 | C11H7KN2O3S2 | 98.000 | [K+].Oc1ccc2nc(sc2c1)C1=N[C@H](CS1)C([O-])=O | 5mg | 808297531](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000126605.jpg-250.jpg)
eMolecules 115144-35-9 | D-Luciferin (potassium) | Medchem Express | MFCD00044928 | 318.410 | C11H7KN2O3S2 | 98.000 | [K+].Oc1ccc2nc(sc2c1)C1=N[C@H](CS1)C([O-])=O | 5mg | 808297531
D-Luciferin (potassium) | Medchem Express | 115144-35-9 | MFCD00044928 | 318.410 | C11H7KN2O3S2 | 98.000 | [K+].Oc1ccc2nc(sc2c1)C1=N[C@H](CS1)C([O-])=O | 5mg | 808297531