Substrates
Apexbio Technology LLC AMC-500MG
AMC (CAS No 26093-31-2) is a compound prevalent in biomedical research especially in the study of enzymatic activity Originating from the need to understand biological pathways AMC serves as a substrate in assays measuring enzyme kinetics and activity It is commonly used in studies involving serine proteases and other peptidases due to its ability to release a fluorescent signal upon enzymatic cleavage allowing researchers to monitor real-time enzyme activity Its effectiveness is often observed in nanomolar to low micromolar ranges making it suitable for high-throughput screening applications AMC is frequently applied in cell models and animal studies to evaluate enzyme inhibitors and explore potential therapeutic pathways Experimental concentrations typically depend on the specific research design highlighting its adaptability in various scientific investigations
Medchemexpress LLC D-luciferin sodium | 103404-75-7 | MFCD00044938 | 99.9% | 302.30 | C11H7N2NaO3S2 | 5MG
D-Luciferin sodium is the sodium salt of D-luciferin, a bioluminescent substrate for firefly luciferase. Upon oxidation in the presence of luciferase, ATP, and oxygen it produces a yellow-green light (peak ~560 nm), making it suitable for sensitive reporter assays and bioluminescence imaging. Supplied as a light-yellow solid with high purity and a defined molecular weight for consistent assay performance.
- High purity for reliable assay results.
- Generates a strong yellow-green bioluminescent signal (peak ~560 nm).
- Suitable for in vitro and in vivo luciferase reporter assays.
- Sodium salt form for good aqueous solubility and easy preparation.
- Supplied in small, accurately weighed quantities for precise dosing.
Medchemexpress LLC D-luciferin potassium | 115144-35-9 | 99.97% | 318.41 g/mol | C11H7KN2O3S2 | 10MM 1ML
D-Luciferin potassium is the potassium salt of D-luciferin, the natural substrate for firefly luciferase. In the presence of luciferase and ATP it produces a yellow-green bioluminescent signal (peak ~560 nm) used for luciferase assays and bioluminescence imaging. Supplied as a 10 mM ready-to-use solution (1 mL), it provides high purity and convenient handling for assay workflows.
- High purity: 99.97% by supplier analysis.
- Ready-to-use 10 mM stock for rapid assay setup.
- Generates strong bioluminescent signal with peak emission near 560 nm.
- Soluble in water (≈54.6 mM) with warming and sonication as needed.
- Suitable for luciferase reporter assays and bioluminescence imaging applications.
- Storage: sealed, protected from moisture and light; in solution store at -80°C for long-term stability.
Medchemexpress LLC Boc-Leu-Lys-Arg-AMC | 109358-47-6 | 96.9% | 672.82 | 1 MG
Boc-Leu-Lys-Arg-AMC is a fluorogenic substrate for the Kex2 endoprotease. It is for research use only and not sold to patients.
- Fluorogenic substrate
- Used for Kex2 endoprotease
- For research use only
- Available in various sizes
- Fluorescent dye
Cayman Chemical Ac-QPKK Ac-AMC 25mg
A fluorogenic substrate for SIRT1, SIRT2, and SIRT3; AMC is released upon enzymatic cleavage by SIRT1, SIRT2, or SIRT3 and its fluorescence can be used to quantify SIRT1, SIRT2, and SIRT3 activity; ex/em = 340-360/440-460 nm, respectively
Enzo Life Sciences Ac-IETD-AMC (1 mg)
Caspase and granzyme substrate. Fluorogenic substrate for caspase-6 and -8 and granzyme B. Also a substrate for caspase-10. Alternative Name: Granzyme B substrate (fluorogenic), Caspase-8 substrate (fluorogenic). Formula: C31H41N5O12. MW: 675.7. Purity: ≥97% (HPLC). Sequence Ac-Ile-Glu-Thr-Asp-AMC (AMC=7-Amino-4-methylcoumarin). Appearance: White to off-white powder. Solubility: Soluble in DMSO. Dilute with buffer, pH 7.5. Long Term Storage: -20°C. Handling: Protect from light. Keep cool and dry.
Carbosynth LLC. 4-Methylumbelliferyl a-D-galactopyranoside | 38597-12-5 | MFCD00063278 | 500 mg
4-Methylumbelliferyl a-D-galactopyranoside | Mol Wt: 338.31 | 38597-12-5 | MFCD00063278 | 500 mg
Enzo Life Sciences Furin convertase substrate (fluorogenic) (5mg). CAS: 136132-77-9
Fluorogenic substrate for furin/SPC1/PACE/PCSK3 and other subtilisin/kexin-like proprotein convertases such as Kex2, SPC2/PC2/PCSK2, SPC3/PCSK1, PACE4/SPC4/PCSK6, SPC5/PC4/PCSK4, SPC6/PC5/PC6/PCSK5, and SPC7/LPC/PC7/PC8/PCSK7. Can be used on live cells. Ex: 360-380 nm, Em: 440-460 nm. Alternative name: Boc-RVRR-AMC, Boc-Arg-Val-Arg-Arg-AMC. Formula: C38H62N14O8. MW: 843.0. Purity: ≥95% (HPLC; TLC). Appearance: White to off-white powder. Solubility: Soluble in water (10mg/ml) or DMSO. Long Term Storage: -20°C. Handling: Protect from light.