Isotopically Labeled Compounds
Sigma Aldrich Fine Chemicals Biosciences L-Serine-13C3,15N 98 atom % 13C, 98 atom % 15N, 95% (CP) | 202407-34-9 | MFCD00144678 | 100MG
L-Serine-13C3,15N 98 atom % 13C, 98 atom % 15N, 95% (CP) | Purity: 95% (CP) | Mol Wt: 109.06 | 202407-34-9 | MFCD00144678 | 100MG
Medchemexpress LLC Adenine-13C | 86967-48-8 | 99.1% | 136.12 g/mol | C5H5N5 (13C-labeled) | 10 MG
Adenine-13C is a stable isotope-labeled adenine (single 13C) supplied as a white to off-white solid for use in mass spectrometry, metabolic tracing, and biochemical assays as an internal standard or tracer. It is intended for research use and should be stored protected from light under inert atmosphere.
- Stable isotope-labeled adenine with a single 13C atom.
- High purity suitable for analytical applications and tracer studies.
- White to off-white solid, easy to weigh and handle.
- Recommended storage: protected from light, under nitrogen, refrigerated or frozen for long-term stability.
- Applications: mass spectrometry internal standard, metabolic flux analysis, and biochemical research.
Medchemexpress LLC Triptolide-d3 | 38748-32-2 | MFCD00210565 | 91.9% | 363.42 g·mol⁻¹ | C20H21D3O6 | 1 MG
Triptolide-d3 (d3) is the deuterium-labeled isotopologue of triptolide supplied as a stable isotope standard for analytical and research applications. It is intended for use as an internal standard or tracer in mass spectrometry and isotopic studies, and is provided in a 1 mg package.
- Deuterium-labeled (d3) isotopologue for internal standard use in mass spectrometry
- Purity 91.9% (>90%)
- Molecular formula C20H21D3O6
- Molecular weight 363.42 g·mol⁻¹
- Package size 1 mg
- Store at -20°C; protect from light; handle under inert atmosphere where indicated
Medchemexpress LLC Dl-dithiothreitol-d6 | 850153-85-4 | MFCD00042404 | 99.0% | 160.29 g·mol-1 | C4H4D6O2S2 | 10 MG
DL-dithiothreitol-d6 (DTT-d6) is the deuterated analogue of DL-dithiothreitol, used as a reducing agent to cleave disulfide bonds and as an isotopic internal standard in analytical and mass spectrometry applications.
- Deuterated (d6) analogue suitable for mass spectrometry and isotopic labeling applications.
- High chemical purity: 99.0%.
- Molecular formula C4H4D6O2S2 and molecular weight 160.29 g·mol-1.
- Used to reduce disulfide bonds in protein and sample preparation workflows.
- Available in 10 mg pack size for analytical use.
Medchemexpress LLC Uridine-1,3-15N2 | 92487-68-8 | 98% | 5 MG
Uridine-15N2 is the 15N labeled Uridine, utilized as a tracer and an internal standard for quantitative analysis using techniques like NMR, GC-MS, or LC-MS. The incorporation of stable heavy isotopes such as hydrogen, carbon, and other elements into drug molecules serves for quantitation during the drug development process. Deuteration has demonstrated the potential to influence the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- For research use only.
Medchemexpress LLC Methyl-warfarin-d3 | 38063-51-3 | 98.0% | 325.37 g·mol⁻1 | C20H15D3O4 | 10 MG
Methyl-warfarin-d3 is a deuterium-labeled methylated analog of warfarin provided as a research-use-only stable isotope reference standard for analytical and method-development applications.
- Deuterium-labeled methyl analog useful as an internal standard.
- High purity suitable for analytical use (≈98.0%).
- Molecular formula C20H15D3O4; molecular weight ~325.37 g·mol⁻1.
- Intended applications: LC-MS, GC-MS, NMR, and method development.
- Supplied as a 10 mg solid for laboratory use (research use only).
Medchemexpress LLC (±)12(13)Epoxy-9Z-octadecenoic-9,10,12,13-d4 acid | 17966-13-1 | 99.0% | 300.47 | 25 UG
(±)12(13)-EpOME-d4 is a deuterium labeled compound designed for research use. It can serve as a tracer and an internal standard in quantitative analysis methods such as NMR, GC-MS, or LC-MS. Deuteration may influence the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer
- Functions as an internal standard for quantitative analysis
- Applicable in NMR, GC-MS, or LC-MS
- Deuterium labeled compound
Medchemexpress LLC (Rac)-DPPC-d6 | 82765-17-1 | 98.0% | 740.08 | 10 MG
This product is a deuterated labeled phosphoglyceride used in lipid research.
- Suitable for lipid research applications.
Cambridge Isotope Laboratories SODIUM ACETATE (2-13C, 99%; D3, 98%), 1 G, 85355-10-8
SODIUM ACETATE (2-13C, 99%; D3, 98%), 1 G, 85355-10-8
Cambridge Isotope Laboratories METHANE (12C, 99.95%; D4, 98%), 1 L, 558-20-3
METHANE (12C, 99.95%; D4, 98%), 1 L, 558-20-3
Cambridge Isotope Laboratories SODIUM ACETATE (1,2-13C2, 99%; D3, 98%), 1 G, 123333-80-2
SODIUM ACETATE (1,2-13C2, 99%; D3, 98%), 1 G, 123333-80-2
Medchemexpress LLC Tamoxifen-d3 hydrochloride | 54965-24-1 | 99.0% | 410.99 | 1 MG
Tamoxifen-d3 hydrochloride is a deuterated labeled Tamoxifen that functions as an orally active, selective estrogen receptor modulator (SERM). It blocks estrogen action in breast cells and activates estrogen activity in other cells, such as bone, liver, and uterine cells. This compound is also a potent Hsp90 activator, enhancing its molecular chaperone ATPase activity. It potently inhibits infectious EBOV Zaire and Marburg (MARV) with IC50 values of 0.1 μM and 1.8 μM, respectively. It activates autophagy and induces apoptosis, and can induce gene knockout of CreER(T2) transgenic mouse.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Nonanoic acid-d2 | 62689-94-5 | 100 MG
Nonanoic acid-d2 is a deuterium-labeled, naturally occurring saturated fatty acid with nine carbon atoms. It reduces bacterial translocation, enhances antibacterial activity, and increases the secretion of porcine β-defensins 1 (pBD-1) and pBD-2. This compound serves as a tracer or internal standard for quantitative analysis methods such as NMR, GC-MS, or LC-MS. Deuterium incorporation in drug molecules allows for tracer applications in drug development, potentially influencing pharmacokinetic and metabolic profiles.
- Deuterium-labeled nonanoic acid
- Reduces bacterial translocation
- Enhances antibacterial activity
- Increases secretion of porcine β-defensins 1 (pBD-1) and pBD-2
- Functions as a tracer in drug development
- Serves as an internal standard for quantitative analysis (NMR, GC-MS, LC-MS)
- May affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC 4h-1-Benzopyran-4-one, 3-(4-hydroxyphenyl)-7-methoxy-d3 | 10 MG
Isoformononetin-d3 is the deuterium labeled Isoformononetin. It is an analog of Daidzein and has immunoprotective effects. Isoformononetin inhibits the differentiation of Th17 and B-cells lymphopoiesis to promote osteogenesis in estrogen-deficient bone loss conditions. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules as tracers for quantitation during drug development. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Deuterium labeled compound
- Analog of daidzein
- Immunoprotective effects
- Inhibits differentiation of Th17 and B-cells lymphopoiesis
- Promotes osteogenesis in estrogen-deficient bone loss conditions
- Used as a tracer for quantitation during drug development
- Potential to affect pharmacokinetic and metabolic profiles of drugs