Isotopically Labeled Compounds
Cambridge Isotope Laboratories ACETIC ACID-D4 (D, 99.5%), 50 G, 1186-52-3
ACETIC ACID-D4 (D, 99.5%), 50 G, 1186-52-3
Medchemexpress LLC Itraconazole-d9 | 1309272-50-1 | 97.9% | 714.69 | 1 MG
Itraconazole-d9 is a deuterium-labeled Itraconazole. It is a triazole antifungal agent and a potent, orally active Hedgehog (Hh) signaling pathway antagonist with an IC50 of approximately 800 nM. It inhibits lanosterol 14α-demethylase (cytochrome P450 enzyme), thereby blocking the oxidative conversion of lanosterol to ergosterol. Itraconazole also exhibits anticancer and antiangiogenic effects and acts as an oxysterol-binding protein (OSBP) inhibitor.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements are incorporated into drug molecules for quantitation during drug development.
- Deuteration can affect pharmacokinetic and metabolic profiles of drugs.
Cambridge Isotope Laboratories 1 6-Dimethylnaphthalene (unlabeled) 50 ug/mL in toluene 1 2 mL
1 6-Dimethylnaphthalene (unlabeled) 50 ug/mL in toluene 1 2 mL
Cambridge Isotope Laboratories 1 8-Dimethylnaphthalene (unlabeled) 50 ug/mL in toluene 1 2 mL
1 8-Dimethylnaphthalene (unlabeled) 50 ug/mL in toluene 1 2 mL
![Revvity Health Sciences Inc Palmitic acid, [1-<sup>14</sup>C]-, 50 µCi](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502811685.jpg-250.jpg)
Medchemexpress LLC Dexamethasone-d3-1 | 50-02-2 | 98.02% | 395.48 | 1 MG
Dexamethasone-d3-1 is a deuterium-labeled Dexamethasone. It acts as a glucocorticoid receptor agonist and is known to decrease CD11b, CD18, and CD62L expression on neutrophils, as well as CD11b and CD18 expression on monocytes. This compound is intended for research use only and can be utilized as a tracer or an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Effective in controlling COVID-19 infection
- Inhibits the production of exosomes containing inflammatory microRNA-155 in lipopolysaccharide-induced macrophage inflammatory responses
Medchemexpress LLC 1-Tetradecanol-d2 | 169398-02-1 | 216.40 | 50 MG
1-Tetradecanol-d2 is the deuterium-labeled derivative of 1-Tetradecanol, a straight-chain saturated fatty alcohol isolated from Myristica fragrans. This compound is known for its antibacterial and anti-inflammatory activities, particularly against periodontitis. It is intended for research use only.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Potential to affect the pharmacokinetic and metabolic profiles of drugs due to deuterium substitution.
Medchemexpress LLC Nicardipine-d3 hydrochloride | 1432061-50-1 | 99.7% | 519.00 | C26H27D3ClN3O6 | 5MG
This deuterium-labeled hydrochloride salt of nicardipine is supplied at high purity as a small-quantity analytical reference for mass spectrometry, method development, and pharmacological research. It provides a stable isotopic standard for accurate quantitation and method verification in analytical workflows.
- High isotopic labeling for accurate mass spectrometry internal standard use.
- High chemical purity suitable for analytical applications.
- Hydrochloride salt form for improved solubility in common solvents.
- Supplied in a small quantity suitable for method development and reference use.
- Appropriate as a reference material for pharmacology and analytical chemistry workflows.
Medchemexpress LLC Sucrose-d14 (D-(+)-Saccharose-d14) | 57-50-1 | 99.0% | 1 MG
Sucrose-d14 is the deuterium labeled Sucrose, a disaccharide composed of two monosaccharides, glucose and fructose. It can be applied in animal models for metabolic disease, obesity, and diet preference. This product serves as a valuable tool for quantitative analysis in various research applications.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuterium substitution can affect the pharmacokinetic and metabolic profiles of drugs.
- Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process.
Cambridge Isotope Laboratories L-GLUTAMIC ACID (2,3,3,4,4-D5, 98%), 0.05 G, 2784-50-1
L-GLUTAMIC ACID (2,3,3,4,4-D5, 98%), 0.05 G, 2784-50-1
Cambridge Isotope Laboratories cis-Permethrin (unlabeled) 50 ug/mL in nonane 1 2 mL
cis-Permethrin (unlabeled) 50 ug/mL in nonane 1 2 mL
Medchemexpress LLC Terconazole-d4 | 1398065-50-3 | 1 MG
Terconazole-d4 is a deuterium-labeled form of Terconazole, a broad-spectrum antifungal medication primarily used for treating vaginal yeast infections. Deuteration may impact the pharmacokinetic and metabolic profiles of the drug.
- Deuterium-labeled compound
- Broad-spectrum antifungal
- Targets fungal pathogens
- Used for vaginal yeast infection treatment
- May affect pharmacokinetic and metabolic profiles
Medchemexpress LLC Adamantane-d16 | 30470-60-1 | 50 MG
Adamantane-d16 is the deuterium-labeled version of Adamantane. Adamantane is a polycyclic cage molecule known for its high symmetry and distinctive properties. It can be incorporated into the lipophilic part of lipid bilayers that form membranes and used as an anchor in the lipid bilayer of liposomes.
- Utilized in research for surface recognition and drug delivery.
- Can be used as a tracer for quantitation during drug development.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuteration has potential to influence the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC L-Glutamic-2,3,3,4,4-d5 acid | 2784-50-1 | 99.8% | 152.16 | 1 ML
L-Glutamic acid-d5 is a deuterium labeled form of L-Glutamic acid. L-Glutamic acid functions as an excitatory transmitter and an agonist at all subtypes of glutamate receptors, including metabotropic, kainate, NMDA, and AMPA receptors. It also directly activates the release of DA from dopaminergic terminals. This product is for research use only and not intended for patient use.
- Deuterium labeled L-Glutamic acid
- Acts as an excitatory transmitter
- Agonist at metabotropic, kainate, NMDA, and AMPA glutamate receptors
- Directly activates DA release from dopaminergic terminals
- Can be used as a tracer
- Suitable as an internal standard for quantitative analysis (NMR, GC-MS, LC-MS)
Cambridge Isotope Laboratories Dimethyl tetrabromobisphenol A (unlabeled) 50 ug/mL in nonane 1 2 mL
Dimethyl tetrabromobisphenol A (unlabeled) 50 ug/mL in nonane 1 2 mL