Isotopically Labeled Compounds
Medchemexpress LLC Bisphenol Z-d6 | 2733972-12-6 | 274.39 | 1 MG
Bisphenol Z-d6 is the deuterium labeled 4,4'-(Cyclohexane-1,1-diyl)diphenol. It is intended for research use only. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Methyl salicylate-d4 | 1219802-12-6 | 156.17 | C8H4D4O3 | 25mg
Methyl Salicylate-d4 is the deuterium labeled Methyl Salicylate[1] Methyl Salicylate (Wintergreen oil) is a topical analgesic and anti-inflammatory agent Also used as a pesticide a denaturant a fragrance ingredient and a flavoring agent in food and tobacco products[2] A systemic acquired resistance (SAR) signal in tobacco[3] A topical nonsteroidal anti-inflammatory agent (NSAID) Methyl salicylate lactoside is a COX inhibitor[5]
Medchemexpress LLC Methyl salicylate-d4 | 1219802-12-6 | >99.0% | 156.17 | C8H4D4O3 | 5mg
Methyl Salicylate-d4 is the deuterium labeled Methyl Salicylate[1] Methyl Salicylate (Wintergreen oil) is a topical analgesic and anti-inflammatory agent Also used as a pesticide a denaturant a fragrance ingredient and a flavoring agent in food and tobacco products[2] A systemic acquired resistance (SAR) signal in tobacco[3] A topical nonsteroidal anti-inflammatory agent (NSAID) Methyl salicylate lactoside is a COX inhibitor[5]
Medchemexpress LLC Methyl salicylate-d4 | 1219802-12-6 | 156.17 g/mol | C8H4D4O3 | 10mg
Methyl Salicylate-d4 is the deuterium labeled Methyl Salicylate[1] Methyl Salicylate (Wintergreen oil) is a topical analgesic and anti-inflammatory agent Also used as a pesticide a denaturant a fragrance ingredient and a flavoring agent in food and tobacco products[2] A systemic acquired resistance (SAR) signal in tobacco[3] A topical nonsteroidal anti-inflammatory agent (NSAID) Methyl salicylate lactoside is a COX inhibitor[5]
Sigma Aldrich Fine Chemicals Biosciences Diethyl phthalate-3,4,5,6-d4 98 atom % D | 93952-12-6 | MFCD00144117 | 250MG
Diethyl phthalate-3,4,5,6-d4 98 atom % D | Mol Wt: 226.26 | 93952-12-6 | MFCD00144117 | 250MG
Sigma Aldrich Fine Chemicals Biosciences Diethyl phthalate-3,4,5,6-d4 98 atom % D | 93952-12-6 | MFCD00144117 | 25MG
Diethyl phthalate-3,4,5,6-d4 98 atom % D | Mol Wt: 226.26 | 93952-12-6 | MFCD00144117 | 25MG
Cambridge Isotope Laboratories CORTISONE (2,2,4,6,6,12,12-D7) 100 UG/ML IN METHANOL, 1 ML, 1261254-36-7
CORTISONE (2,2,4,6,6,12,12-D7) 100 UG/ML IN METHANOL, 1 ML, 1261254-36-7
Cambridge Isotope Laboratories CORTISONE (2,2,4,6,6,9,12,12-D8, 98%), 5 MG
CORTISONE (2,2,4,6,6,9,12,12-D8, 98%), 5 MG
Cambridge Isotope Laboratories CORTISONE (2,2,4,6,6,9,12,12-D8, 98%), 1 MG
CORTISONE (2,2,4,6,6,9,12,12-D8, 98%), 1 MG
Cambridge Isotope Laboratories Ethanol (1 2-13C2 99%) 6% water 0 25 g
Ethanol (1 2-13C2 99%) 6% water 0 25 g
Medchemexpress LLC Ranolazine-d3 | 1054624-77-9 | 99.5% | 100 MG
Ranolazine-d3 is a deuterium labeled anti-angina agent that inhibits the late phase of inward sodium current (INa and IKr with IC50 values of 6 μM and 12 μM, respectively) without affecting heart rate or blood pressure. It also functions as a partial fatty acid oxidation inhibitor and is intended for research use only.
- Used as a tracer.
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Ranolazine-d3 | 1054624-77-9 | 99.5% | 50 MG
Ranolazine-d3 is the deuterium labeled Ranolazine, which is known as an anti-angina agent (CVT 303). It functions by inhibiting the late phase of inward sodium current (INa and IKr) at IC50 values of 6 μM and 12 μM, respectively, without influencing heart rate or blood pressure. Additionally, it serves as a partial fatty acid oxidation (FAO) inhibitor and an antianginal agent.
- Used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuterium substitution can affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC N-(2,6-dimethylphenyl)-2-(4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)piperazin-1-yl-2,2,3,3,5,5,6,6-d8)acetamide dihydrochloride | 1219802-60-4 | 99.0% | 508.51 | 1 MG
Ranolazine-d8 (dihydrochloride) is the deuterium labeled Ranolazine dihydrochloride. Ranolazine dihydrochloride (CVT 303 dihydrochloride) is an anti-angina agent that achieves its effects by inhibiting the late phase of inward sodium current (INa and IKr with IC50 values of 6 μM and 12 μM, respectively) without affecting heart rate or blood pressure (BP). Ranolazine dihydrochloride is also a partial fatty acid oxidation inhibitor. It is for research use only and not sold to patients.
- Isotope-labeled compounds
- Hot research area
- Internal standard for clinical mass spectrometry
- Isotope-labeled inhibitors
- Deuterium (2H, D) stable isotope-labeled inhibitors
- Stable isotope-labeled inhibitors for use in in vivo cell experiments
- Therapeutic drug monitoring: TDM
Medchemexpress LLC Ranolazine-d3 | 1054624-77-9 | 99.5% | 5 MG
Ranolazine-d3 is the deuterium labeled Ranolazine. Ranolazine (CVT 303) is an anti-angina agent that achieves its effects by inhibiting the late phase of inward sodium current (INa and IKr with IC50 values of 6 μM and 12 μM, respectively) without affecting heart rate or blood pressure (BP). Ranolazine is also a partial fatty acid oxidation (FAO) inhibitor. It is an antianginal agent. It is for research use only and not sold to patients.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.