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Karl Fischer Buffers and Reagents

Buffers and reagents intended for use with Karl Fischer (KF) titration techniques. KF titration is a classic titration method that uses coulometric or volumetric titration to determine the moisture content of a sample.

Karl Fischer (KF) reagents are used in the analytical technique developed by chemist Karl Fischer to accurately measure the water content of gases, liquids, and solids.

Key applications include:

  • Analyzing water content in raw materials and finished products
  • Estimating moisture in food, pharmaceuticals, chemicals, and petroleum products
  • Determining the water content of laboratory samples.

Karl Fischer reagents contain a variety of chemicals in proprietary formulations. Consult the SDS for individual products for appropriate handling instructions and precautions.

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1 – 15 of 379 results
1

Karl Fischer Aqualine™ Matrix K, for Karl Fischer Titration By Volumetry, Fisher Chemical™

EDGE
MDL Number 81734
Color Colorless
Packaging Amber glass bottle
Physical Form Liquid
2

HYDRANAL™ - Composite 2, Reagent for volumetric one-component Karl Fischer titration (methanol free), Solstice
BIOPHARMA GSA_VA

EDGE
CAS 111-90-0
5

HYDRANAL™ - Composite 5, Reagent for volumetric one-component Karl Fischer titration (methanol free), Solstice
BIOPHARMA GSA_VA

EDGE
CAS 111-90-0
6

HYDRANAL™ - Water Standard 0.1 PC, Standard for Karl Fischer titration (water content 0.1 mg/g = 0.01%), verified against NIST SRM 2890 and NMIJ CRM 4222, Solstice
GSA_VA

Molecular Formula: C4H6O3 Molecular Weight (g/mol): 102.09 MDL Number: MFCD00005385,MFCD00798264,MFCD00798265 InChI Key: RUOJZAUFBMNUDX-UHFFFAOYNA-N PubChem CID: 7924 IUPAC Name: 4-methyl-1,3-dioxolan-2-one SMILES: CC1COC(=O)O1

EDGE
PubChem CID 7924
Molecular Weight (g/mol) 102.09
MDL Number MFCD00005385,MFCD00798264,MFCD00798265
SMILES CC1COC(=O)O1
IUPAC Name 4-methyl-1,3-dioxolan-2-one
InChI Key RUOJZAUFBMNUDX-UHFFFAOYNA-N
Molecular Formula C4H6O3
7

Karl Fischer Aqualine™ Electrolyte AG, for Karl Fischer Titration By Coulometry, Fisher Chemical™

Nonhalogenated anolyte solution for general use in conventional cells with a diaphragm

8

HYDRANAL™-Composite 1, Titrating agent for volumetric one-component Karl Fischer titration (methanol free), Solstice

Molecular Formula: C3H5IN2 Molecular Weight (g/mol): 195.99 InChI Key: JBOIAZWJIACNJF-UHFFFAOYSA-N IUPAC Name: 1H-imidazole hydroiodide SMILES: I.N1C=CN=C1

EDGE
Molecular Weight (g/mol) 195.99
SMILES I.N1C=CN=C1
IUPAC Name 1H-imidazole hydroiodide
InChI Key JBOIAZWJIACNJF-UHFFFAOYSA-N
Molecular Formula C3H5IN2
9

Karl Fischer Aqualine™ Complete 5, for Karl Fischer Titration By Volumetry, Fisher Chemical™

Single-component reagent; Pyridine free

Name Note Karl Fischer Reagent
CAS 7553-09-5
Health Hazard 3 Emergency Overview
Causes burns by all exposure routes. Harmful by inhalation. Possible risk of harm to the unborn child.
NFPA
Health:
Health Hazard 2 DANGER!
Color Brown
Physical Form Liquid
Health Hazard 1 Signal Word: DANGER!
Chemical Name or Material Aqualine™ Complete 5
Cleanup Symbol Solvent
ChemAlert Storage Symbol Gray
10

Karl Fischer Aqualine™ Water Standard 10mg, for Karl Fischer Titration, Fisher Chemical

Molecular Formula: C4H10O Molecular Weight (g/mol): 74.123 MDL Number: 240423 InChI Key: LRHPLDYGYMQRHN-UHFFFAOYSA-N PubChem CID: 263 ChEBI: CHEBI:28885 IUPAC Name: butan-1-ol SMILES: CCCCO

PubChem CID 263
Molecular Weight (g/mol) 74.123
ChEBI CHEBI:28885
MDL Number 240423
SMILES CCCCO
IUPAC Name butan-1-ol
InChI Key LRHPLDYGYMQRHN-UHFFFAOYSA-N
Molecular Formula C4H10O
11

Aqualine™ Complete 2, Fisher Chemical™

Single-component reagent; Pyridine free

Physical Form Liquid
14

Karl Fischer Solvent, solvent for volumetric two-component titration, Thermo Scientific Chemicals

Boiling Point 65°C
Name Note solvent for volumetric two-component titration
Health Hazard 3 P201-P202-P210-P233-P235-P240-P241-P242-P243-P260-P264b-P270-P271-P281-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P370+P378q-P501c
Health Hazard 2 GHS H Statement
H225-H311-H331-H370-H314-H302
Highly flammable liquid and vapor.
Toxic in contact with skin.
Toxic if inhaled.
Causes damage to organs.
Causes severe skin burns and eye damage.
Harmful if swallowed.
Color Colorless to Green
Physical Form Liquid
Health Hazard 1 H225-H301+H311+H331-H314-H335-H360D-H370
UN Number UN3286
DOT Information Transport Hazard Class: 3; Packaging Group: II; Proper Shipping Name: FLAMMABLE LIQUID, TOXIC, CORROSIVE, N.O.S.
Chemical Name or Material Karl Fischer Solvent
TSCA Yes
Recommended Storage Ambient temperatures
Density 0.910 g/mL
15

HYDRANAL™ - Coulomat AG-Oven, Reagent for coulometric KF titration with oven (anolyte solution), for cells with and without diaphragm, Solstice
BIOPHARMA GSA_VA

Boiling Point 64°C
CAS Min % ≥20.0000%
UN Number UN1230
Chemical Name or Material HYDRANAL™ - Coulomat AG-Oven
Grade Karl Fischer
Density 0.980 g/cm3
Name Note Reagent for coulometric KF titration with oven (anolyte solution), for cells with and without diaphragm
CAS 57-55-6
Packaging Glass Bottle
Flash Point 13°C
DOT Information Transport Hazard Class: 3; Packing Group:3: II; Proper Shipping Name: Methanol Solution
Recommended Storage Room Temp
Shelf Life 1800 days from date of manufacture
CAS Max % <10.0000%