Cullin 4A/4B Antibody (YA2583) is a Rabbit-derived, non-conjugated IgG monoclonal antibody that targets Cullin 4A/4B. It serves as a core component of multiple cullin-RING-based E3 ubiquitin-protein ligase complexes, facilitating ubiquitination and proteasomal degradation of target proteins. These complexes play roles in DNA repair/replication, regulate G1/S transition, and mTORC1 signaling.
- Rabbit-derived, non-conjugated IgG monoclonal antibody
- Targets Cullin 4A/4B
- Reactivity: Human, Hamster, Rat
- Applications: WB, IHC-P
- Supplied as a liquid
- Affinity purified
- Storage at -20°C for 1 year
- Avoid repeated freeze/thaw cycles
- Molecular weight: 104 kDa (predicted)