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Molecular sieves are materials with pores of uniform size and diameter that are similar in size to small molecules; used to separate molecules by size; available in various pore size ranges, with drying solvent indicators, etc.
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TCS-PIM-1-4a is a small-molecule inhibitor targeting Pim kinases a family of serine/threonine kinases It is designed to selectively inhibit Pim kinases thereby modulating signaling pathways related to cell growth and survival TCS-PIM-1-4a exerts its biological activity primarily through activation of AMP-activated protein kinase (AMPK) resulting in inhibition of the mammalian target of rapamycin complex 1 (mTORC1) signaling pathway In cell-based studies TCS-PIM-1-4a demonstrates cytotoxic activity against diverse hematological tumor cell lines including myeloid and lymphoid subtypes with IC50 values ranging from approximately 0 8 to 40 M Based on these pharmacological properties TCS-PIM-1-4a holds research potential in investigations of Pim kinase signaling and therapeutic strategies for hematological malignancies
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
AVG-233 is a potent, orally active RNA-dependent RNA polymerase (RdRp) inhibitor used for research into respiratory syncytial virus (RSV). It prevents initiation of the viral polymerase complex and shows nanomolar activity against RSV strains and clinical isolates.
Potent RNA-dependent RNA polymerase inhibitor.
Reported EC50 = 0.14-0.31 μM against RSV strains and clinical isolates.
Molecular formula: C26H22ClN5O3.
Molecular weight: 487.94 g/mol.
Available as a solid in multiple pack sizes (5 mg-500 mg).
Intended for research use only; not for human or diagnostic use.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More