Siliconizing Fluids
Thermo Scientific™ Water-Soluble Siliconizing Fluid
To siliconize glass surfaces use Thermo Scientific™ Water-Soluble Siliconizing Fluid.
Thermo Scientific™ Hydrocarbon Soluble Siliconizing Fluid
For siliconizing glass surfaces use Thermo Scientific™ Hydrocarbon Soluble Siliconizing Fluid.
Apexbio Technology LLC PMX 205 Trifluoroacetate 514814-49-4 (free base) 1mg
PMX 205 Trifluoroacetate is a cyclic hexapeptide antagonist targeting the complement C5a receptor (C5aR CD88) It is designed to competitively inhibit C5a binding to its receptor thereby modulating complement-mediated inflammatory pathways PMX 205 Trifluoroacetate exerts its biological activity primarily through competitive antagonism at C5aR reducing downstream inflammatory cellular responses In animal models PMX 205 Trifluoroacetate demonstrates anti-inflammatory effects Based on these pharmacological properties PMX 205 Trifluoroacetate holds research potential in the study of neuroinflammation Alzheimer s disease and chemically induced colitis
Medchemexpress LLC (E)-AG 556 (E)-Tyrphostin AG 556 | 133550-41-1 | 99.9% | 336.39 g/mol | C20H20N2O3 | 50 MG
(E)-AG 556 is a small-molecule research compound that selectively inhibits the epidermal growth factor receptor (EGFR) and reduces LPS-induced tumor necrosis factor-alpha (TNF-α) production. It is supplied as a high-purity solid intended for biochemical and cellular studies of EGFR signaling and inflammation pathways.
- Highly selective EGFR inhibitor.
- Reduces LPS-induced TNF-α production in cellular assays.
- High purity suitable for research applications.
- Characterized chemical with CAS 133550-41-1 for unambiguous identification.
- Supplied in a small-pack solid form for laboratory use.
eMolecules Oakwood Chemicals Glycerin USP grade 20kg 480152364 102072 0 000 56-81-5 MFCD00004722 92 094 C3H8O3
Oakwood Chemicals Glycerin USP grade 20kg 480152364 102072 0 000 56-81-5 MFCD00004722 92 094 C3H8O3
Medchemexpress LLC (E)-AG 556 | 133550-41-1 | >98.0% | 336.39 g/mol | C20H20N2O3 | 25 MG
(E)-AG 556 is a research-grade small molecule that selectively inhibits epidermal growth factor receptor (EGFR) activity and has been reported to block lipopolysaccharide (LPS)-induced tumor necrosis factor-α (TNF-α) production. It is supplied as a solid powder for use in biochemical and cellular assays and is intended for research use only.
- Selective EGFR inhibition for targeted signaling studies.
- Reported to reduce LPS-induced TNF-α production in cellular models.
- Powder form suitable for preparation of stock solutions and dosing.
- High purity appropriate for biochemical and cellular assays.
- Recommended long-term storage at -20°C to preserve stability.
Medchemexpress LLC PMX-53 | 219639-75-5 | MFCD07363866 | 99.9% | 896.09 | C47H65N11O7 | 50 MG
PMX-53 is a synthetic peptidic antagonist of the complement C5a receptor (C5aR1/CD88). It is orally active and is used in preclinical research on inflammation, cancer, and atherosclerosis. Reported potency at C5aR1 is approximately 20 nM, and analytical data and storage recommendations are provided with the product documentation.
- Peptidic C5a receptor antagonist.
- Orally active, suitable for in vivo and in vitro studies.
- Potent activity against C5aR1 (IC50 ≈ 20 nM).
- Selective for C5aR1 over C5L2 and C3aR.
- Characterized sequence and molecular weight for analytical use.
- COA available with storage recommendations to preserve stability.
Medchemexpress LLC Pmx-53 (Ac-Phe-{Orn}-Pro-{dCha}-Trp-Arg lactam) | 219639-75-5 | 99.9% | 896.09 g/mol | C47H65N11O7 | 100 MG
PMX-53 is a synthetic peptidic research compound that functions as a potent, orally active antagonist of the complement C5a receptor (C5aR1/CD88). It selectively binds C5aR1, displays low-affinity agonism at MrgX2, and is used in preclinical studies of inflammation, nociception, cancer, and atherosclerosis.
- Potent complement C5a receptor antagonist (IC50 = 20 nM).
- Inhibits C5a-induced neutrophil myeloperoxidase release (IC50 = 22 nM).
- Inhibits C5a-induced neutrophil chemotaxis (IC50 = 75 nM).
- Low-affinity MrgX2 agonist that can induce mast cell degranulation.
- Peptidic sequence: Ac-Phe-{Orn}-Pro-{dCha}-Trp-Arg with Orn2-Arg6 lactam bridge.
- Molecular formula C47H65N11O7; molecular weight 896.09 g/mol.
- Available in small research pack sizes for in vitro and in vivo studies.
