Antibody-Binding Proteins and Conjugates
Cayman Chemical Fluorescent BrIghtenr 28 500mg
An active metabolite of progesterone increases intracellular calcium levels in washed isolated human platelets at 10 UM
Cayman Chemical MonsInsodIum salt 500mg
A biguanide with diverse biological activities increases hepatic AMPK activity and reduces blood glucose by more than 50 in a liver kinase B1-dependent manner in mice fed normal and high-fat diets respectively and reduces blood glucose by 40 in ob/ob mice at 250 mg/kg reduces weight gain hepatic lipid droplet content and total cholesterol LDL cholesterol and triglyceride levels in the plasma of diet-induced obese mice at 10 or 50 mg/kg per day reverses increased hepatic triglyceride and apolipoprotein A5 levels as well as hepatic steatosis in an ob/ob mouse model of NAFLD reduces tumor growth in an HCT116 p53-\- mouse xenograft model at 250 mg/kg
Cayman Chemical CItIcolInsodIum salt 500mg
A selective inhibitor of matrix metalloproteinase-2 (MMP-2) demonstrating an IC50 value of 12 nM significantly less potent towards MMP-1 MMP-3 MMP-7 and MMP-9 (IC50 50 4.5 50 and 0.2 UM respectively) suppresses invasive behavior of HT1080 tumor cells grown on matrigel at 50 nM
Cayman Chemical on-AE3-208sodIum salt 50mg
A metal ion chelator used in zinc treatment studies to limit intra- and extracellular concentrations of the minerial
Cayman Chemical RaltegravIrpotasIum salt 50mg
Antigen full length human TRF2 Host goat Cross Reactivity human and mouse TRF2 Application(s) ChIP ICC IF IHC IP and WB TRF2 is a ubiquitously expressed protein that is implicated in the control of telomere length.
Cayman Chemical CItIcolInsodIum salt 50mg
An inhibitor of HDACs that preferentially inhibits HDAC1 (IC50 300 nM) over HDAC3 (IC50 8 M) does not inhibit HDAC8 induces p21/CIP1/WAF1 slowing cell growth differentiation and tumor development in vivo
Cayman Chemical CntharIdIc AcIdodIum salt 50mg
A pyrazine benzamide that prevents activation of all three isoforms of PKD in endothelial cells treated with VEGF (IC50s 1 2 and 1 5 nM for PKD1 PKD2 and PKD3 respectively) decreases VEGF-induced endothelial migration proliferation and tubulogenesis
Cayman Chemical RhodamIn 101Inr salt 500mg
A coniferyl ester that acts as a partial agonist of TRPV1 (EC50 3 2 UM) eliciting only 20 of the maximum response induced by capsaicin
Cayman Chemical MethIcIlInsodIum salt 50mg
A coenzyme that is tightly bound to enzymes catalyzing oxidation and reduction reactions in a variety of biosynthetic pathways binds the FMN riboswitch (RFN element) on RNA to alter gene regulation a substrate of FMN phosphohydrolases
Cayman Chemical UDPD-GlucosesodIum salt 500mg
A non-selectiveBadrenergic receptor blocker that acts on both B1 and B2 receptors
Cayman Chemical ON-01910sodIum salt 25mg
A bicyclic CB analog with potent analgesic activity comparable or more potent than 9-THC in analgesic motor depressant anticonvulsant and hypothermic effects avidly binds the CB1 receptor (Ki 4.15 nM).
Cayman Chemical PIcosulfatSodIM salt hydr 50mg
An analytical reference standard that is structurally similar to known synthetic cannabinoids a potential metabolite of 5-fluoro EMB-PICA intended for research and forensic applications
Cell Signaling Technology FGF Receptor 1 D8E4 XPR Rabbit mAb PE Conjugate 100 ul
FGF Receptor 1 D8E4 XPR Rabbit mAb PE Conjugate 100 ul
Cayman Chemical ngelIs Salt 50mg
An inhibitor of PARP14 MD2 binds to PARP14 MD2 (Kd 860 nM) inhibits PARP14 MD2 relocalization to the sites of DNA damage in U2OS cells at 50 UM
Cayman Chemical TalaporfInsodIum salt 50mg
A chelating agent selective for calcium over magnesium with Kapp values for calcium ranging from 6 93 to 10 7 x 105 M-1 in various buffers at pH 6 8 and 20 C inhibits apoptosis induced by thapsigargin in isolated rat thymocytes at 5 mM has been used as an irrigation agent to remove the smear layer from the pulp canal wall on extracted human teeth intranasal administration enhances adenovirus-mediated gene transfer of LacZ to the trachea and main bronchi in mice by 8-fold