Native Proteins and Derivatives
Biotium MAP3K1 (Mitogen-Activated Protein Kinase Kinase Kinase 1)(2F6), CF488A conjugate, 0.1mg/mL
Mitogen-activated protein (MAP) kinase cascades are activated by various extracellular stimuli, including growth factors. The MEK kinases (also designated MAP kinase kinase kinases, MKKKs, MAP3Ks or MEKKs) phosphorylate and thereby activate the MEKs (also called MAP kinase kinases or MKKs), including ERK, JNK and p38. These activated MEKs in turn phosphorylate and activate the MAP kinases. The MEK kinases include Raf-1, Raf-B, Mos, MEK kinase-1, MEK kinase-2, MEK kinase-3, MEK kinase-4 and ASK 1 (MEK kinase- 5). MEK kinase-1 activates the ERK and c-Jun NH2-terminal kinase (JNK) pathways by phosphorylation of MAP2K1 and MAP2K4, and also activates the central protein kinases of the NFB pathway, CHUK and IKBKB. Additionally, MEK kinase-1 uses an E3 ligase through its PHD domain, a RING-finger-like structure, to target proteins for degradation through ubiquitination.
ILEX LIFE SCIENCES LLC PORCINE THROMBIN PROTEIN 500 U
Ilex Life Sciences Thrombin Porcine, Purified Protein (500 U). DESCRIPTION: Thrombin Porcine, purified native enzyme, lyophilized. CAS REGISTRY NO.: 9002-04-4. FORMULATION: Sterile filtered white lyophilized (freeze-dried) powder. Lyophilized powder from glycine, calcium chloride pH 7.0 containing 0.9% NaCl. OTHER NAMES: Native thrombin protein, Porcine Activated Factor IIa, Factor 2A, F2, PT, RPRGL2, THPH1, coagulation factor II, EC 3.4.21.5, UniProtKB# P00735. APPLICATION: As a result of its high proteolytic specificity, thrombin has become an important biochemical protein. The thrombin cleavage site (Leu-Val-Pro-Arg-Gly-Ser) is widely used in linker regions of recombinant fusion protein constructs. After the purification of the fusion protein, thrombin is used to cleave between the Arginine and Glycine residues of the cleavage site, efficiently removing the purification tag from the protein of interest with a high degree of specificity.
American Research Products Inc Pig plasminogen actiVator inhi
Pig plasminogen actiVator inhibitor 1 PAI-1 ELISA Kit from CUSABIO Detection Range 0 312 ng/mL-20 ng/mL Sensitivity 0 078 ng/mL Sample serum plasma tissue homogenates Method Sandwich
Cayman Chemical GypenosIde IX 50mg
A dammarane-type triterpene saponin; prevents increases in iNOS, IL-6, and TNF-α levels, as well as phosphorylation of NF-κB, IκB, p38 MAPK, and Akt, induced by LPS and TNF-α in rat C6 glial at 25 μM; reduces LPS-induced increases in NF-κB, IκB, p38 MAPK, and Akt phosphorylation in mouse brain cortex at 30 mg/kg per day
Medchemexpress LLC PLAU/uPA Mouse HEK 100ug | 100ug
PLAU or urokinase-type plasminogen activator (uPA) critically initiates fibrinolysis by cleaving plasminogen to form active plasmin This enzymatic conversion is critical for regulating clot dissolution and tissue remodeling PLAU/uPA Protein Mouse (HEK293 C-His-Avi) is the recombinant mouse-derived PLAU/uPA protein expressed by HEK293 with C-His-Avi labeled tag
Cayman Chemical SARSCoV2B 1 1 7Alpha Va 96
Cayman’s SARS-CoV-2 (B.1.1.7, Alpha Variant) Neutralizing Antibody SimpleDetect ELISA Kit is a competitive assay that can be used for qualitative and/or semi-quantitative measurement of neutralizing antibodies in human plasma and serum. The assay has a range of 7.81-1,000 ng/ml, with a midpoint (50% B/B0) of 100-160 ng/ml, and a sensitivity (80% B/B0) of approximately 49 ng/ml.
Bioss Fibronectin Cell/Heparin2 Bind
Fibronectin (Cell/Heparin2 Binding region) Primary Antibody Unconjugated Host Species Mouse Target Species Human Clonality Monoclonal Applications WB IP M013Concentration Size 100 ul Storage Buffer PBS 1 mg/ml BSA 0 05% NaN3 and 50% glycerol