Native Proteins and Derivatives
Cayman Chemical GunosIn 5thIotrIphosp 2.7mg
A hydrolysis-resistant analog of GTP; binds to and activates G proteins in the presence of magnesium; has been used to obtain crystal structures of GTPases in their active states, as well as measure the stability of GTPases in the presence of ligands; [35S]GTPγS is commonly used in binding assays to determine agonism or antagonism at GPCRs
Cayman Chemical 2 3O 6AmInohexylcarbamo 3.3mg
A mixture of GTP derivatives; has been used in the synthesis of europium (III) chelates for use in QRET assays in the study of GTPase nucleotide exchange kinetics
Abcam PD 150606, Calpain inhibitor, 25MG
MW 306.12 Da, Purity >98%. Potent, selective and cell-permeable Ca²+-dependent calpain inhibitor (Ki values are 210 and 370 nM for calpain-1 and calpain-2 respectively). Non-competitive and non-peptide. Irreversibly inhibits ICa through AMPA receptors. Anti-ischemic effects in vivo. .
The product is subject to the following: Abcam Restricted Use Statement
Abcam PD 150606, Calpain inhibitor, 5MG
MW 306.12 Da, Purity >98%. Potent, selective and cell-permeable Ca²+-dependent calpain inhibitor (Ki values are 210 and 370 nM for calpain-1 and calpain-2 respectively). Non-competitive and non-peptide. Irreversibly inhibits ICa through AMPA receptors. Anti-ischemic effects in vivo. .
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical 2OMethylgunosIn5OtrI 2.7mg
An HCV NS5B inhibitor (IC50 = 3.5 µM) and active metabolite of IDX184; induces tubulin polymerization at 50 µM; tumoral levels are decreased in patients with hepatocellular carcinoma compared with adjacent normal tissue
Abcam Native E. coli beta Galactosidase protein, 1MG
Native E. coli beta Galactosidase protein is a Escherichia coli K-12 Full Length protein, expressed in Escherichia coli, with >97% purity and suitable for IA.
Protein/ Peptide/ Enzyme Synonyms: b0344, JW0335, lacZ, Beta-galactosidase, Beta-gal, Lactase
Conjugation: Unconjugated
The product is subject to the following: Abcam Restricted Use Statement
Abcam NYC-488, Calpain Inhibitor, calpain inhibitor, 1MG
MW 460.4 Da, Purity >94%. Novel, selective calpain inhibitor. Possible therapeutic agent against Alzheimer's disease.
The product is subject to the following: Abcam Restricted Use Statement
Sigma Aldrich Fine Chemicals Biosciences fibronectin bovine plasma1MG
fibronectin is a glycoprotein with multiple domains. It comprises a N-terminal central binding domain and a heparin-binding domain. Bovine plasma fibronectin has polypeptide chains with disulfide linkage and corresponds to a molecular weight of 220 and 215 kDa.
ABclonal Technology ApoB Rabbit pAb
This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins (LDL), and is the ligand for the LDL receptor. It occurs in plasma as two main isoforms, apoB-48 and apoB-100 the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->,UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels.
Abcam Diclofenac sodium salt, cyclo-o x ygenase inhibitor, 1G
MW 318.13 g/mol, Purity >99%. Potent non-selective COX inhibitor (IC₅₀ values are 75 and 29 nM at COX-1 and COX-2, respectively). Potent inhibitor of phospholipase A₂ in vitro and in vivo. Activates the nitric oxide-cyclic GMP-potassium channel pathway. Shows anti-inflammatory, antipyretic and analgesic effects.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Sitagliptin Phosphate Monohydrate, 100MG
MW 523.32 Da, Purity >=98%. Anti-diabetic (antihyperglycemic) drug of the dipeptidyl peptidase-4 (DPP-4) class. Inhibition of the enzyme DPP-4 is thought to increase Glucagon-like peptide-1 (GLP-1) which inhibits glucagon release , stimulates the insulin release and lowers blood glucose.
The product is subject to the following: Abcam Restricted Use Statement
Bioss KD-Validated Calpain 2 Rabbit
Calpain 2 Primary Antibody Unconjugated Public Immunogen Range 657-700/700 Host Species Rabbit Target Species Human Clonality Monoclonal Applications WB FCM IC Concentration Lot dependent Size 50 ul Storage Buffer Supplied in PBS (pH 7 4) containing 50% glycerol and 0 02% sodium azide
Sigma Aldrich Fine Chemicals Biosciences Tissue plasminogen activat1MG
Tissue plasminogen activator (tPA) is a protease of the S1 family (trypsin family) and is found in a wide variety of mammalian tissues especially endothelial cells. tPA is secreted as a single chain precursor which is cleaved to a two-chain form by plasmin. Supplied in the single chain form with a molecular weight of ~70nbspkDa. The Tissue Plasminogen Activator (tPA) gene is mapped to human chromosome 8p11.21 and encodes a protease of 69nbspkDa majorly containing serine amino acid residue. It is predominantly expressed in endothelial cells.
Abcam Native Human Ceruloplasmin protein, 1MG
Native Human Ceruloplasmin protein is a Human Full Length protein, expressed in Mammalian, with >=95% purity and suitable for SDS-PAGE.
Protein/ Peptide/ Enzyme Synonyms: Ceruloplasmin, Cuproxidase ceruloplasmin, Ferroxidase ceruloplasmin, Glutathione peroxidase ceruloplasmin, Glutathione-dependent peroxiredoxin ceruloplasmin, CP
Conjugation: Unconjugated
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical 3AmIno3deoxyadenosIn5 2.1mg
An amine-modified nucleotide; has been used in the synthesis of fluorescently labeled ADP; has been used in the synthesis of phosphorylated probes for GTP pyrophosphokinase domains