Apoptosis Reagents and Kits

BD Annexin V: PE Apoptosis Detection Kit I Available on GSA/VA Contract for Federal Government customers only.

Contains apoptotic program characterized by certain morphologic features, including loss of plasma membrane asymmetry and attachment, condensation of the cytoplasm and nucleus, and internucleosomal cleavage of DNA

R&D Systems Caspase-3 Colorimetric Assay Kit

Plate-based assay uses a peptide coupled to a colorimetric reporter system to assess activity in cell lysates

BD Pharmingen™ Yellow-Green Live Cell Caspase Probe

Cells with active caspases can be detected. BD Pharmingen™ Yellow-Green Live Cell Caspase Probe contains a fluorochrome-labeled caspase inhibitor. Fluorochrome-labeled caspase inhibitors have three functional domains: fluorochrome , 3-amino acid sequence (VAD) that binds to the active site of the activated caspase, and fluoromethyl ketone (FMK) moiety that allows the probe to irreversibly bind the active caspase.

BD Phospholipid-binding Protein, APC Annexin V Available on GSA/VA Contract for Federal Government customers only.

Has high affinity for PS, and binds to cells with exposed PS

R&D Systems Caspase-8 Colorimetric Assay Kit

Plate-based assay uses a peptide coupled to a colorimetric reporter system to assess activity in cell lysates

BD Pharmingen™ Violet Live Cell Caspase Probe

Cells with active caspases can be detected. BD Pharmingen™ Violet Live Cell Caspase Probe contains a fluorochrome-labeled caspase inhibitor. Fluorochrome-labeled caspase inhibitors have three functional domains: fluorochrome , 3-amino acid sequence (VAD) that binds to the active site of the activated caspase, and fluoromethyl ketone (FMK) moiety that allows the probe to irreversibly bind the active caspase.

R&D Systems DePsipher™ Mitochondrial Potential Kit

Can be used to evaluate the viability of a cell population, quickly estimate the effect of drugs or other cytotoxins on a cell population, and detect early apoptosis in known models

BD Annexin V-PE Available on GSA/VA Contract for Federal Government customers only.

Serves as a sensitive probe for flow cytometric analysis of cells that are undergoing apoptosis

R&D Systems Poly(ADP-ribose) (PAR) Polymer/pADPr

Synthesized using poly(ADP-ribose) polymerase (PARP-1) in the presence of NAD, cleaved from PARP-1, and purified by gel filtration

BD Apoptosis Detection Kit (APO-Direct) Available on GSA/VA Contract for Federal Government customers only.

Single-step staining method for labeling DNA breaks to detect apoptotic cells by flow cytometry.

R&D Systems Caspase-9 Fluorometric Assay Kit

Plate-based assay uses a peptide coupled to a fluorometric reporter system to assess activity in cell lysates

R&D Systems Caspase-9 Colorimetric Assay Kit

Plate-based assay uses a peptide coupled to a colorimetric reporter system to assess activity in cell lysates

BD Annexin V-FITC Available on GSA/VA Contract for Federal Government customers only.

Serves as a sensitive probe for flow cytometric analysis of cells that are undergoing apoptosis

R&D Systems HT Homogeneous PARG Chemiluminescent Inhibition Assay

A highly sensitive high-throughput chemiluminescence screening assay for PARG inhibitors in vitro

R&D Systems TACS TdT In Situ Apoptosis Detection Kit, Blue Label

A TUNEL assay designed for fixed cells, embedded tissue, and frozen tissue using light and electron microscopy

R&D Systems CometAssay™ High Throughput Slides

Provides convenient, simple and reliable sample preparation, processing, analysis and storage

R&D Systems TACS TdT In Situ Apoptosis Detection Kit, Fluorescein

A TUNEL assay designed for fixed cells, embedded tissue, and frozen tissue using fluorescence microscopy

BD Annexin V-V450 Available on GSA/VA Contract for Federal Government customers only.

Serves as a sensitive probe for flow cytometric analysis of cells that are undergoing apoptosis

R&D Systems TACS DNA Laddering Kit Lysis Solution 1

For use with TACS DNA Laddering Kit in visualizing DNA framentation in apoptosis

R&D Systems CometAssay Lysis Solution

For use in apoptosis detection applications

R&D Systems Caspase-3 Fluorometric Assay Kit

Plate-based assay uses a peptide coupled to a fluorometric reporter system to assess activity in cell lysates

R&D Systems Magnesium cation

Suitable for use with TdT apoptosis or DNA damage and repair kits

BD Annexin V: FITC Apoptosis Detection Kit I Available on GSA/VA Contract for Federal Government customers only.

Staining precedes the loss of membrane integrity which accompanies the latest stages of cell death resulting from either apoptotic or necrotic processes

R&D Systems FlowTACS™ Flow Cytometry Apoptosis Detection Kit

Supplied with a streptavidin-FITC conjugate for detection of DNA fragmentation providing a fluorescent readout

R&D Systems TACS Annexin V-Biotin Apoptosis Detection Kit

Offers flexibility in labeling by allowing the use of streptavidin-conjugated fluorophores other than FITC for detection

R&D Systems TACS 2 TdT Replinisher Kit

Provides only reagents most rapidly exhausted from the complete TACS 2 TdT kits

R&D Systems CometAssay™ 96 Single-Cell Gel Electrophoresis Assay

Relies on a specially treated 96-well slide to promote adherence of low melting point agarose, shortening the overall assay time

Novus Biologicals™ Caspase Apoptosis Kit

Detect active caspases with Flow Cytometry, in vitro assay, or fluorophore-linked immunosorbent assay.

R&D Systems Cytonin

Use in dual-labeling experiments detecting both DNA fragmentation and antigens that may be sensitive to proteinase K treatment. Cytonin can be used to permeabilize cells and tissues prior to labeling with TACS™ in situ Apoptosis Detection Kits.

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