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alpha-Smooth Muscle Actin Antibody (ACTA2/791) - IHC-Prediluted, Novus Biologicals™
SDP

Catalog No. NBP248132 Shop All R&D Systems Products
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NBP248132 7 mL
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Catalog No. NBP248132 Supplier Novus Biologicals Supplier No. NBP248132
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Description

Mouse Monoclonal Antibody

alpha-Smooth Muscle Actin Monoclonal specifically detects alpha-Smooth Muscle Actin in Human, Rat samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

Antigen alpha-Smooth Muscle Actin
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone ACTA2/791
Conjugate Unconjugated
Dilution Immunohistochemistry-Paraffin
Formulation 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Alias AAT6, actin, alpha 2, smooth muscle, aorta, actin, aortic smooth muscle, ACTSA, ACTVS, alpha 2 actin, alpha SMA, alpha smooth muscle actin, alpha-actin-2, alpha-SMA, a-sma, Cell growth-inhibiting gene 46 protein, growth-inhibiting gene 46, sma, smooth muscle actin
Gene Symbols ACTA2
Host Species Mouse
Immunogen Recombinant full-length human alpha-Smooth Muscle Actin protein (Uniprot: P62736)
Molecular Weight of Antigen 42 kDa
Purification Method Protein A or G purified
Quantity 7 mL
Regulatory Status RUO
Research Discipline Angiogenesis, Cancer, Cardiovascular Biology, Cell Biology, Cellular Markers, Developmental Biology, Extracellular Matrix, Signal Transduction, Stem Cell Markers
Primary or Secondary Primary
Gene ID (Entrez) 59
Test Specificity Actin is a major component of the cytoskeleton and is present in most cell types. It is highly specific to actin from smooth muscles. This monoclonal antibody does not stain cardiac or skeletal muscle; however, it does stain myofibroblasts and myoepithelial cells. This antibody could be used together with anti-muscle specific actin and myogenin in making a diagnosis of smooth muscle and skeletal muscle tumors. In most cases of rhabdomyosarcoma, this antibody yields negative results whereas anti-muscle specific actin and myogenin are positive. Leiomyosarcomas are positive only with anti-muscle specific actin and anti-smooth muscle actin and are negative with anti-myogenin.
Target Species Human, Rat
Content And Storage Store at 4C.
Form Purified
Isotype IgG2a κ
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