Amylin Monoclonal Antibody (C2), Invitrogen™

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
PIMA543964	Invitrogen™ MA543964	20 μL
PIMA543963	Invitrogen™ MA543963	100 μL

Description

The target peptide sequence is KCNTATCATQRLANFLV.

Islet, or insulinoma, amyloid polypeptide is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the association of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Studies suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes.

Specifications

• Antigen: Amylin
• Concentration: 1 mg/mL
• Classification: Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300
• Gene Alias: Amylin; amylin peptide; DAP; Diabetes-associated peptide; IAP; Iapp; Insulinoma amyloid peptide; islet amyloid polypeptide; Islet amyloid polypeptide (diabetes-associated peptide; amylin); Rabbit Anti-Amylin
• Gene Symbols: IAPP
• Isotype: IgG2a κ
• Purification Method: Protein A/G
• Product Type: Antibody

• Clone: C2
• Applications: Immunohistochemistry (Paraffin)
• Conjugate: Unconjugated
• Host Species: Mouse
• Target Species: Human
• Gene Accession No.: P10997
• Gene ID (Entrez): 3375
• Immunogen: Recombinant Amylin (Lys34-Val50).
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: IAPP