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Annexin II Mouse, Unlabeled, Clone: 5, BD

Mouse Monoclonal Antibody

$286.00 - $566.00

Specifications

Antigen Annexin II
Clone 5
Concentration 250μg/mL
Applications Western Blot
Classification Monoclonal
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
BDB610068
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BD Biosciences
610068
50 μg
Each for $286.00
Only null left
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BDB610069
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BD Biosciences
610069
150 μg
Each for $566.00
Only null left
Add to Cart
 
Description

Description

Annexin II (p36), originally discovered as a substrate for the src oncogene, is one of the most studied members of the annexin family of calcium-dependent phospholipid-binding proteins. It exists in cells as either a monomer or a heterotetramer complexed with p11, an S100-related protein. In vitro, it has been found that unphosphorylated annexin II is capable of causing aggregation of chromaffin granules, and, upon phosphorylation, induces fusion of the granules membranes. A similiar phenomenon may occur in the final steps of exocytosis after cytoplasmic annexin translocates to the subplasmalemmal region and is phosphorylated by protein kinase C. However, other studies refute annexin II's involvement in exocytosis, and a conclusive role for annexin II in membrane trafficking remains debated.

Host Species: Mouse
Clone: 5
Isotype: IgG1
Species Reactivity: Human
Immunogen: Human Annexin II aa. 123-328
Formula Weight [Chemical]: 36kDa

Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting

Specifications

Specifications

Annexin II
250μg/mL
Monoclonal
Mouse
Cell Biology
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
IgG1
Affinity Purified
Lipocortin II, Calpactin I
5
Western Blot
Unconjugated
RUO
Canine, Chicken, Human, Mouse, Rat
Human Annexin II aa. 123-328
Primary
Store undiluted at -20°C.
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