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γ-Catenin Mouse, Unlabeled, Clone: 15, BD

Mouse Monoclonal Antibody

$287.50 - $526.00

Specifications

Antigen γ-Catenin
Clone 15
Concentration 250μg/mL
Applications Western Blot
Classification Monoclonal
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
BDB610253
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BD Biosciences
610253
50 μg
Each for $287.50
Only null left
Add to Cart
 
BDB610254
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BD Biosciences
610254
150 μg
Each for $526.00
Only null left
Add to Cart
 
Description

Description

γ-Catenin (plakoglobin) was identified as a compenent of desmosomes where it associates with desmoglein. γ-Catenin and β-Catenin are closely related proteins that have significant homology with the Drosophila armadillo protein. In addition to complexing with E-Cadherin, γ-Catenin and β-Catenin have been observed in association with the intracellular domain of N-Cadherin. It has been proposed that one molecule of α-Catenin and at least one molecule of β-Catenin and γ-Catenin simultaneously bind to a single cadherin molecule. A 19 amino acid sequence of desmoglein (Dsg1) was found to be critical for binding of γ-Catenin. This region has significant homology to the catenin-binding domain of classical cadherins, thus suggesting a common mechanism for γ-Catenin localization at both adherens junctions and desmosomes.

Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting

Specifications

Specifications

γ-Catenin
250μg/mL
Monoclonal
Mouse
Cell Biology
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
IgG2a
Affinity Purified
15
Western Blot
Unconjugated
RUO
Canine, Chicken, Human, Mouse, Rat
Human γ-Catenin aa. 553-738
Primary
Store undiluted at -20°C.
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Documents

Product Certifications

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