Learn More
Fibronectin Mouse, Unlabeled, Clone: 10, BD
Mouse Monoclonal Antibody
$237.00 - $458.00
Specifications
| Antigen | Fibronectin |
|---|---|
| Isotype | IgG1, κ |
| Immunogen | Human Fibronectin |
| Formulation | Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. |
| Conjugate | Unconjugated |
Description
The 240kDa dimeric fibronectin protein exists in two forms: a soluble protomer in body fluids and an insoluble multimer in the extracellular matrix. The latter is the primary functional form and creates a substrate for cell migration, a role which makes fibronectin vital to embryogenesis and wound response. Fibronectin mediates cytoskeletal organization, cell attachment, and cellular signaling through interactions with cellular receptors. Although various isoforms of fibronectin are derived by alternative splicing, they share a common N-terminus which is a critical region for cell surface binding in an initial step of multimer assembly. Further polymerization steps are regulated by fibronectin/integrin interactions and result in generation of the complex fibrils that constitute the fibronectin matrix.
Host Species: Mouse
Clone: 10
Isotype: IgG1
Species Reactivity: Human
Immunogen: Human Fibronectin
Formula Weight [Chemical]: 240kDa
Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting
Specifications
| Fibronectin | |
| Human Fibronectin | |
| Unconjugated | |
| Cell Biology | |
| Mouse | |
| Affinity Purified | |
| Monoclonal | |
| FN; LETS |
| IgG1, κ | |
| Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. | |
| Primary | |
| Flow Cytometry | |
| RUO | |
| 10 | |
| 250μg/mL | |
| Store undiluted at -20°C. |
For Research Use Only.
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.