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CD68/SR-D1 Antibody (C68/684), DyLight 550, Novus Biologicals™
SDP

Catalog No. NBP234587R Shop All R&D Systems Products
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Description

Mouse Monoclonal Antibody

CD68/SR-D1 Monoclonal specifically detects CD68/SR-D1 in Human, Mouse, Rat, Monkey samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

Specifications

Antigen CD68/SR-D1
Applications Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Classification Monoclonal
Clone C68/684
Conjugate DyLight 550
Dilution Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Alias CD68 antigenmacrophage antigen CD68, CD68 molecule, DKFZp686M18236, GP110, macrosialin, SCARD1, scavenger receptor class D, member 1
Gene Symbols CD68
Host Species Mouse
Immunogen Recombinant human CD68/SR-D1 protein (Uniprot: P34810)
Molecular Weight of Antigen 110 kDa
Purification Method Protein A or G purified
Quantity 0.1 mL
Regulatory Status RUO
Research Discipline Cell Biology, Cytokine Research, Immunology, Microglia Markers
Primary or Secondary Primary
Gene ID (Entrez) 968
Test Specificity This antibody recognizes a glycoprotein of 110kDa, which is identified as CD68. It is important for identifying macrophages in tissue sections. It stains macrophages in a wide variety of human tissues, including Kupffer cells and macrophages in the red pulp of the spleen, in lamina propria of the gut, in lung alveoli, and in bone marrow. It reacts with myeloid precursors and peripheral blood granulocytes. It also reacts with plasmacytoid T cells, which are supposed to be of monocyte/macrophage origin. It shows strong granular cytoplasmic staining of chronic and acute myeloid leukemia and also reacts with rare cases of true histiocyticneoplasia. Lymphomas are negative or show few granules.
Target Species Human, Mouse, Feline, Primate, Rat (Negative)
Content And Storage Store at 4C in the dark.
Form Purified
Isotype IgG1 κ
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