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EGFR Antibody (B1D8), DyLight 405, Novus Biologicals™
SDP

Catalog No. NBP234553V Shop All R&D Systems Products
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Description

Mouse Monoclonal Antibody

EGFR Monoclonal specifically detects EGFR in Human, Mouse (Negative), Rat (Negative) samples. It is validated for Flow Cytometry.

Specifications

Antigen EGFR
Applications Flow Cytometry
Classification Monoclonal
Clone B1D8
Conjugate DyLight 405
Dilution Flow Cytometry
Gene Alias avian erythroblastic leukemia viral (v-erb-b) oncogene homolog, cell growth inhibiting protein 40, cell proliferation-inducing protein 61, EC 2.7.10, EC 2.7.10.1, epidermal growth factor receptor, epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b)oncogene homolog), ERBB, ErbB1, ERBB1PIG61, HER1, mENA, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1
Gene Symbols EGFR
Host Species Mouse
Immunogen Microsomes from A431 cells
Purification Method Protein A or G purified
Quantity 0.1 mL
Regulatory Status RUO
Research Discipline Cancer, Cell Biology, Cell Cycle and Replication, Cellular Markers, Cellular Signaling, Growth and Development, Hypoxia, Phospho Specific, Signal Transduction, Tumor Suppressors, Tyrosine Kinases
Primary or Secondary Primary
Gene ID (Entrez) 1956
Test Specificity This antibody reacts with the extracellular domain of EGFR and blocks the EGF/TGF'induced activation. It also blocks tumor growth in vivo. It is excellent for purification of EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin.
Target Species Human, Mouse (Negative), Rat (Negative)
Content And Storage Store at 4C in the dark.
Form Purified
Isotype IgG2a κ
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