beta 2-Microglobulin Antibody (B2M/1118), Novus Biologicals™

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
NBP24446700	Novus Biologicals NBP2444670.02MG	0.02 mg
NBP24446701	Novus Biologicals NBP2444670.1MG	0.1 mg
NBP24446702	Novus Biologicals NBP2444670.2MG	0.2 mg

Description

Ensure accurate, reproducible results in Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence

beta 2-Microglobulin Monoclonal specifically detects beta 2-Microglobulin in Human, Primate samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunofluorescence.

Specifications

• Antigen: beta 2-Microglobulin
• Concentration: 0.2mg/mL
• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
• Conjugate: Unconjugated
• Host Species: Mouse
• Research Discipline: Adaptive Immunity, Cancer, Cell Biology, Diabetes Research, Immunology
• Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
• Gene Alias: beta chain of MHC class I molecules, beta-2-microglobin, beta-2-microglobulin
• Gene Symbols: B2M
• Isotype: IgG1 κ
• Purification Method: Protein A or G purified
• Test Specificity: beta 2 microglobulin is a 12KDa protein with a pI of 5.6. Serum beta 2 microglobulin levels are a reflection of cell turnover. Levels rise with fever, inflammation, and infection. Increased serum levels are also seen in B-cell malignancies and in renal failure and may indicate a worse prognosis for patients with early-stage Hodgkin's lymphoma. In urine, increased levels are seen in proximal renal tubular disease as well as renal transplant rejection. beta 2 microglobulin levels can rise either because its rate of synthesis has increased (e.g. in AIDS, malignant monoclonal plasma cell dyscrasia, solid tumours and autoimmune disease) or because of impaired renal filtration (e.g. due to renal insufficiency, graft rejection or nephrotoxicity induced by post-transplantation immunosuppressive therapy).

• Clone: B2M/1118
• Dilution: Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml
• Classification: Monoclonal
• Form: Purified
• Regulatory Status: RUO
• Target Species: Human, Primate
• Gene Accession No.: P61769
• Gene ID (Entrez): 567
• Immunogen: Full length recombinant human B2M protein
• Primary or Secondary: Primary
• Content And Storage: Store at 4C.
• Molecular Weight of Antigen: 12 kDa

For Research Use Only