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c-Myb Antibody (MYB286), Novus Biologicals™
SDP

Catalog No. p-7105372 Shop All R&D Systems Products
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0.02 mg
0.1 mg
0.2 mg
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Catalog No. Quantity
NBP232837F 0.02 mg
NBP232837A 0.1 mg
NBP232837B 0.2 mg
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Catalog No. NBP232837F Supplier Novus Biologicals Supplier No. NBP2328370.02MG
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Description

Mouse Monoclonal Antibody

c-Myb Monoclonal specifically detects c-Myb in Human samples. It is validated for ELISA.

Specifications

Antigen c-Myb
Applications Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation
Classification Monoclonal
Clone MYB286
Conjugate Unconjugated
Dilution Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunoprecipitation 0.5-1ug/500ug protein lysate
Formulation PBS with 0.05% BSA. with 0.05% Sodium Azide
Gene Accession No. P10242
Gene Alias c-myb, Cmyb, c-myb protein (140 AA), c-myb_CDS, c-myb10A_CDS, c-myb13A_CDS, c-myb14A_CDS, c-myb8B_CDS, efg, Proto-oncogene c-Myb, transcriptional activator Myb, v-myb avian myeloblastosis viral oncogene homolog, v-myb myeloblastosis viral oncogene homolog (avian)
Gene Symbols MYB
Host Species Mouse
Immunogen A synthetic peptide, corresponding to aa 119-135 (RRKVEQEGYPQESSKAG) of c-myb oncoprotein, coupled to KLH
Molecular Weight of Antigen 75 kDa
Purification Method Protein A purified
Quantity 0.02 mg
Regulatory Status RUO
Research Discipline Cancer, Phospho Specific
Primary or Secondary Primary
Gene ID (Entrez) 4602
Test Specificity The highly leukemogenic avian retrovirus E26 contains two oncogenes, v-Myb and v-Ets, which are expressed together as a fusion protein. The cellular homolog of v-Myb, designated c-Myb, encodes a transcription factor. Deletion or disruption of a negative regulatory domain mapping within the carboxy-terminal domain of c-Myb results in enhanced transactivating capacity and in parallel, leads to activation of its ability to transform hemopoietic cells. c-Myb is expressed preferentially, but not exclusively, in immature hemopoietic cells and its expression decreases as cells differentiate.
Target Species Human
Content And Storage Store at 4C.
Form Purified
Isotype IgG1 κ
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