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CD19 Antibody (CVID3/155), FITC, Novus Biologicals™
SDP

Catalog No. NBP261908F Shop All R&D Systems Products
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NBP2-61908F 0.1 mL
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Catalog No. NBP2-61908F Supplier Novus Biologicals Supplier No. NBP261908F
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Description

Mouse Monoclonal Antibody

CD19 Monoclonal specifically detects CD19 in Human, Monkey samples. It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence.

Specifications

Antigen CD19
Applications Flow Cytometry, Immunocytochemistry, Immunofluorescence
Classification Monoclonal
Clone CVID3/155
Conjugate FITC
Dilution Flow Cytometry, Immunocytochemistry/Immunofluorescence
Formulation PBS with 0.05% Sodium Azide
Gene Alias B4, B-lymphocyte antigen CD19, B-lymphocyte surface antigen B4, CD19 antigen, CD19 molecule, CVID3, Differentiation antigen CD19, MGC12802, T-cell surface antigen Leu-12
Gene Symbols CD19
Host Species Mouse
Immunogen Recombinant full-length human CD19 protein (Uniprot: P15391 )
Purification Method Protein A or G purified
Quantity 0.1 mL
Research Discipline Adaptive Immunity, B Cell Development and Differentiation Markers, Cytokine Research, Immunology, Innate Immunity, Mesenchymal Stem Cell Markers, Myeloid derived Suppressor Cell, Signal Transduction, Stem Cell Lines, Stem Cell Markers
Primary or Secondary Primary
Gene ID (Entrez) 930
Test Specificity Recognizes a protein of 95kDa, identified as CD19. CD19 is a transmembrane glycoprotein that contains two extracellular immunoglobulin-like domains. CD19 is present in both benign and malignant B-cells and is considered to be the most reliable surface marker of this lineage over a wide range of maturational stages. In normal lymphoid tissue, CD19 is observed in germinal centers, in mantle zone cells, and in scattered cells of the inter-follicular areas. Anti-CD19 exhibits an overall immunoreactivity pattern similar to those of the antibodies against CD20 and CD22. However, in contrast to CD20, expression of CD19 is continuous throughout B-cell development and through terminal differentiation of B-cells into plasma cells. Anti-CD19 positivity is seen in the vast majority of B-cell neoplasms commonly at a lower intensity than normal B-cell counterparts. Plasma cell neoplasms are nearly always negative, as are T-cell neoplasms.
Target Species Human, Monkey
Content And Storage Store at 4°C in the dark.
Isotype IgG1 κ
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