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CD1a Antibody (CB-T6), Novus Biologicals™
SDP

Catalog No. p-5539189 Shop All R&D Systems Products
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Catalog No. Quantity
NBP24524200 0.02 mg
NBP24524201 0.1 mg
NBP24524202 0.2 mg
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Catalog No. NBP24524200 Supplier Novus Biologicals Supplier No. NBP2452420.02MG
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Description

Mouse Monoclonal Antibody

Ensure accurate, reproducible results in Flow Cytometry, Immunofluorescence

CD1a Monoclonal specifically detects CD1a in Human, Mouse samples. It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunofluorescence.

Specifications

Antigen CD1a
Applications Flow Cytometry, Immunofluorescence
Classification Monoclonal
Clone CBT6
Concentration 0.2 mg/mL
Conjugate Unconjugated
Dilution Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunofluorescence 1 - 2 ug/ml
Formulation 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Alias CD1, CD1a antigen, CD1A antigen, a polypeptide, CD1a molecule, cluster of differentiation 1 A, cortical thymocyte antigen CD1A, differentiation antigen CD1-alpha-3, epidermal dendritic cell marker CD1a, FCB6, HTA1, hTa1 thymocyte antigen, R4, T6, T-cell surface antigen T6/Leu-6, T-cell surface glycoprotein CD1a
Gene Symbols CD1A
Host Species Mouse
Immunogen Human CD1a
Molecular Weight of Antigen 49 kDa
Purification Method Protein A or G purified
Quantity 0.02 mg
Regulatory Status RUO
Research Discipline Dendritic Cell Markers, Immunology
Primary or Secondary Primary
Gene ID (Entrez) 909
Test Specificity At least five CD1 genes (CD1a, b, c, d, and e) are identified. CD1 proteins have been demonstrated to restrict T cell response to non-peptide lipid and glycolipid antigens and play a role in non-classical antigen presentation. CD1a is a non-polymorphic MHC Class 1 related cell surface glycoprotein, expressed in association with Beta-2 microglobulin. Anti-CD1a labels Langerhans cell histiocytosis (Histiocytosis X), extranodal histiocytic sarcoma, a subset of T-lymphoblastic lymphoma/leukemia, and interdigitating dendritic cell sarcoma of the lymph node. When combined with antibodies against TTF-1 and CD5, anti-CD1a is useful in distinguishing between pulmonary and thymic neoplasms since CD1a is consistently expressed in thymic lymphocytes in both typical and atypical thymomas, but only focally in 1/6 of thymic carcinomas and not in lymphocytes in pulmonary neoplasms. Anti-CD1a is reported to be a new marker for perivascular epithelial cell tumor (PEComa).
Target Species Human, Mouse
Content And Storage Store at 4C.
Form Purified
Isotype IgG1 κ
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For Research Use Only

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