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CD30/TNFRSF8 Antibody (Ber-H2), Novus Biologicals™
SDP

Catalog No. NBP24455901 Shop All R&D Systems Products
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NBP24455905 0.5 mL
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Catalog No. NBP24455901 Supplier Novus Biologicals Supplier No. NBP2445590.1ML
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Description

Mouse Monoclonal Antibody

Ensure accurate, reproducible results in Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence

CD30/TNFRSF8 Monoclonal specifically detects CD30/TNFRSF8 in Human samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

Antigen CD30/TNFRSF8
Applications Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Classification Monoclonal
Clone Ber-H2
Concentration 0.2mg/mL
Conjugate Unconjugated
Dilution Flow Cytometry 5 - 10 ul/million cells in 0.1ml, Immunohistochemistry, Immunohistochemistry-Paraffin 1:50 - 1:100, Immunofluorescence 1:50 - 1:100
Formulation No buffer with 0.05% Sodium Azide
Gene Accession No. P28908, P28908
Gene Alias CD30, CD30 antigen, CD30KI-1, CD30L receptor, cytokine receptor CD30, D1S166EKi-1, Ki-1 antigen, Lymphocyte activation antigen CD30, tumor necrosis factor receptor superfamily member 8, tumor necrosis factor receptor superfamily, member 8
Gene Symbols TNFRSF8
Host Species Mouse
Immunogen Co cell line established from a patient with Hodgkin s disease of T-cell lineage
Purification Method Tissue culture supernatant
Quantity 0.1 mL
Regulatory Status RUO
Research Discipline Apoptosis, Cell Cycle and Replication, Embryonic Stem Cell Markers, Immunology, Stem Cell Markers
Primary or Secondary Primary
Gene ID (Entrez) 943
Test Specificity Recognizes a single chain glycoprotein of 105/120kDa, identified as CD30/Ki-1. Its epitope is located between aa112-412. CD30 is synthesized as a 90kDa precursor, which is processed in the Golgi complex into a membrane-bound phosphorylated mature 105/120kDa glycoprotein. In Hodgkin s disease, CD30/Ki-1 antigen is expressed by mononuclear-Hodgkin and multinucleated Reed-Sternberg cells. It is also expressed by the tumor cells of a majority of anaplastic large cell lymphomas as well as by a varying proportion of activated T and B cells. This MAb distinguishes large cell lymphomas derived from activated lymphoid cells from histiocytic malignancies and lymphomas derived from resting and precursor lymphoid cells or from anaplastic carcinomas. About one third of the Ki-1 positive lymphomas lack the leukocyte common antigen (CD45).
Target Species Human
Content And Storage Store at 4C.
Form Supernatant
Isotype IgG1 κ
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For Research Use Only

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