CD30/TNFRSF8 Antibody (Ber-H2), Novus Biologicals™

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
NBP24455901	Novus Biologicals NBP2445590.1ML	0.1 mL
NBP24455905	Novus Biologicals NBP2445590.5ML	0.5 mL

Description

Ensure accurate, reproducible results in Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence

CD30/TNFRSF8 Monoclonal specifically detects CD30/TNFRSF8 in Human samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

• Antigen: CD30/TNFRSF8
• Concentration: 0.2mg/mL
• Applications: Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
• Conjugate: Unconjugated
• Host Species: Mouse
• Research Discipline: Apoptosis, Cell Cycle and Replication, Embryonic Stem Cell Markers, Immunology, Stem Cell Markers
• Formulation: No buffer with 0.05% Sodium Azide
• Gene Alias: CD30, CD30 antigen, CD30KI-1, CD30L receptor, cytokine receptor CD30, D1S166EKi-1, Ki-1 antigen, Lymphocyte activation antigen CD30, tumor necrosis factor receptor superfamily member 8, tumor necrosis factor receptor superfamily, member 8
• Gene Symbols: TNFRSF8
• Isotype: IgG1 κ
• Purification Method: Tissue culture supernatant
• Test Specificity: Recognizes a single chain glycoprotein of 105/120kDa, identified as CD30/Ki-1. Its epitope is located between aa112-412. CD30 is synthesized as a 90kDa precursor, which is processed in the Golgi complex into a membrane-bound phosphorylated mature 105/120kDa glycoprotein. In Hodgkin s disease, CD30/Ki-1 antigen is expressed by mononuclear-Hodgkin and multinucleated Reed-Sternberg cells. It is also expressed by the tumor cells of a majority of anaplastic large cell lymphomas as well as by a varying proportion of activated T and B cells. This MAb distinguishes large cell lymphomas derived from activated lymphoid cells from histiocytic malignancies and lymphomas derived from resting and precursor lymphoid cells or from anaplastic carcinomas. About one third of the Ki-1 positive lymphomas lack the leukocyte common antigen (CD45).

• Clone: Ber-H2
• Dilution: Flow Cytometry 5 - 10 ul/million cells in 0.1ml, Immunohistochemistry, Immunohistochemistry-Paraffin 1:50 - 1:100, Immunofluorescence 1:50 - 1:100
• Classification: Monoclonal
• Form: Supernatant
• Regulatory Status: RUO
• Target Species: Human
• Gene Accession No.: P28908, P28908
• Gene ID (Entrez): 943
• Immunogen: Co cell line established from a patient with Hodgkin s disease of T-cell lineage
• Primary or Secondary: Primary
• Content And Storage: Store at 4C.

For Research Use Only