CD86 Mouse anti-Rat, FITC, Clone: 24F, BD

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
BDB561961	BD Biosciences 561961	50 μg
BDB555018	BD Biosciences 555018	0.5 mg

Description

The 24F antibody reacts with CD86 (B7-2), a member of the Ig superfamily of transmembrane proteins. CD86, a ligand for CD28 and CD152 (CTLA-4), is one of the accessory molecules that plays an important role in T cell-B cell costimulatory interactions. CD86 is predominantly expressed on antigen-presenting cells. It can be upregulated on splenic B cells by in vitro polyclonal activation, such as LPS treatment. 24F mAb is reported to block the costimulatory function of rat CD86 and to immunoprecipitate CD86 from Lewis-S1 cell lysates.HTLV-1-transformed rat T-cell line Lewis-S1

This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

Specifications

• Antigen: CD86
• Concentration: 0.5mg/mL
• Classification: Monoclonal
• Host Species: Mouse
• Target Species: Rat
• Isotype: IgG1 κ
• Purification Method: Affinity Purified
• Description: B7-2

• Clone: 24F
• Applications: Flow Cytometry
• Conjugate: FITC
• Regulatory Status: RUO
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

For Research Use Only.