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  6. Cytochrome b245 alpha Antibody (CS9) - BSA Free, Novus Biologicals™

Cytochrome b245 alpha Antibody (CS9) - BSA Free, Novus Biologicals™
SDP

Catalog No. p-7200750 Shop All R&D Systems Products
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0.025 mg
0.1 mg
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Catalog No. Quantity
NB018514 0.025 mg
NBP14097401 0.1 mg
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Catalog No. NB018514 Supplier Novus Biologicals Supplier No. NBP1409740.025MG
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Description

Mouse Monoclonal Antibody

Cytochrome b245 alpha Monoclonal specifically detects Cytochrome b245 alpha in Human samples. It is validated for Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunoprecipitation, Immunohistochemistry-Frozen.

Specifications

Antigen Cytochrome b245 alpha
Applications ELISA, Immunohistochemistry (Frozen), Flow Cytometry, Immunoprecipitation, Western Blot, Immunohistochemistry
Classification Monoclonal
Clone CS9
Concentration 1.0 mg/mL
Conjugate Unconjugated
Dilution Western Blot 1:100-1:2000, Flow Cytometry 1:10-1:100, ELISA 1:100-1:2000, Immunohistochemistry 1:10-1:500, Immunoprecipitation 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500
Formulation PBS (pH 7.4) with 0.09% Sodium Azide
Gene Accession No. P13498
Gene Alias cytochrome b light chain, Cytochrome b(558) alpha chain, cytochrome b(558) alpha-subunit, cytochrome b, alpha polypeptide, cytochrome b-245 light chain, cytochrome b-245, alpha polypeptide, Cytochrome b558 subunit alpha, flavocytochrome b-558 alpha polypeptide, Neutrophil cytochrome b 22 kDa polypeptide, p22 phagocyte B-cytochrome, p22phox, p22-phox, Superoxide-generating NADPH oxidase light chain subunit
Gene Symbols CYBA
Host Species Mouse
Immunogen Cytochrome B245 solubilised in octyl-beta-gluycopyranoside
Purification Method Protein G purified
Quantity 0.025 mg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1535
Test Specificity This antibody recognizes the light chain of cytochrome B245, also known as p22phox, a subunit of the nicotinamide adenine dinucleotide phosphate-oxidase (NADPH oxidase). NADPH oxidase is a membrane-bound enzyme complex in neutrophils that produces the superoxide anion (O2-) by transferring single electrons from NADPH inside the cell across the membrane and coupling them to molecular oxygen. Superoxide is used for the destruction of pathogens. Individuals with defects in NADPH oxidase suffer from chronic granulomatous disease, characterized by severe recurrent infections.
Target Species Human
Content And Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Form Purified
Isotype IgG1
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