Cytokeratin 18 Antibody (DC10), DyLight 755, Novus Biologicals™

Catalog No.	Quantity
NBP233082IR	0.1 mL

Catalog No. NBP233082IR Supplier Novus Biologicals Supplier No. NBP233082IR

Description

Mouse Monoclonal Antibody

Cytokeratin 18 Monoclonal specifically detects Cytokeratin 18 in Human, Bovine (Negative), Canine (Negative), Hamster (Negative), Mouse (Negative), Porcine (Negative), Rat (Negative), Sheep (Negative) samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

Specifications

• Antigen: Cytokeratin 18
• Applications: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
• Classification: Monoclonal
• Clone: DC10
• Conjugate: DyLight 755
• Dilution: Western Blot 1:100-1:2000, Flow Cytometry 1:10-1:1000, ELISA 1-5 μg/mL for coating, Immunohistochemistry 1:10-1:500, Immunocytochemistry/Immunofluorescence 1:10-1:500, Immunohistochemistry-Paraffin 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500
• Gene Alias: Cell proliferation-inducing gene 46 protein, cell proliferation-inducing protein 46, CK-18, CYK18, cytokeratin 18, cytokeratin-18, K18, keratin 18, keratin, type I cytoskeletal 18, keratin-18
• Gene Symbols: KRT18
• Host Species: Mouse
• Immunogen: Human breast cancer PMC 42 cells were used as immunogen to generate the Keratin 18 antibody.
• Molecular Weight of Antigen: 45 kDa
• Purification Method: Protein A or G purified
• Quantity: 0.1 mL
• Regulatory Status: RUO
• Research Discipline: Cancer, Cell Biology, Cellular Markers, Cytoskeleton Markers, Phospho Specific
• Primary or Secondary: Primary
• Gene ID (Entrez): 3875
• Test Specificity: This monoclonal antibody reacts with a wide variety of simple epithelia. It does not react with stratified squamous epithelia. It reacts with epithelial tumors of the gastrointestinal tract, lung, breast, pancreas, ovary, and thyroid. Cytokeratin 18, which belongs to the type A (acidic) subfamily of low molecular weight keratins, exists in combination with cytokeratin 8. It is reported that tissues from gastrointestinal tract are positive for both cytokeratin 8 and 18 but do not contain cytokeratin 14. Tissues from gastrointestinal tract, respiratory tract and urogenital tract, as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18.
• Target Species: Human, Bovine (Negative), Canine (Negative), Hamster (Negative), Mouse (Negative), Porcine (Negative), Rat (Negative)
• Content And Storage: Store at 4C in the dark.
• Form: Purified
• Isotype: IgG1 κ

For Research Use Only