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Cytokeratin 18 Antibody (KRT18/835), Alexa Fluor™ 750, Novus Biologicals™
SDP

Catalog No. NP247986A70 Shop All R&D Systems Products
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NP247986A70 0.1 mL
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Catalog No. NP247986A70 Supplier Novus Biologicals Supplier No. NBP247986AF750
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Description

Mouse Monoclonal Antibody

Cytokeratin 18 Monoclonal specifically detects Cytokeratin 18 in Human, Bovine (Negative), Canine (Negative), Hamster (Negative), Porcine (Negative), Rat (Negative), Sheep (Negative) samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence.

Specifications

Antigen Cytokeratin 18
Applications Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Classification Monoclonal
Clone KRT18/835
Conjugate Alexa Fluor 750
Dilution Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
Formulation 50 mM sodium borate with 0.05% sodium azide
Gene Alias Cell proliferation-inducing gene 46 protein, cell proliferation-inducing protein 46, CK-18, CYK18, cytokeratin 18, cytokeratin-18, K18, keratin 18, keratin, type I cytoskeletal 18, keratin-18
Gene Symbols KRT18
Host Species Mouse
Immunogen Recombinant full-length human Cytokeratin 18 protein (Uniprot: P05783)
Purification Method Protein A or G purified
Quantity 0.1 mL
Research Discipline Cancer, Cell Biology, Cellular Markers, Cytoskeleton Markers, Phospho Specific
Primary or Secondary Primary
Gene ID (Entrez) 3875.0
Test Specificity This monoclonal antibody reacts with a wide variety of simple epithelia. It does not react with stratified squamous epithelia. It reacts with epithelial tumors of the gastrointestinal tract, lung, breast, pancreas, ovary, and thyroid. Cytokeratin 18, which belongs to the type A (acidic) subfamily of low molecular weight keratins, exists in combination with cytokeratin 8. It is reported that tissues from gastrointestinal tract are positive for both cytokeratin 8 and 18 but do not contain cytokeratin 14. Tissues from gastrointestinal tract, respiratory tract and urogenital tract, as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18.
Target Species Human, Bovine, Canine, Hamster, Mouse, Pig, Rat, Sheep
Content And Storage Store at 4°C in the dark.
Isotype IgG1 κ
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