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Cytokeratin 7 Antibody (KRT7/760), Alexa Fluor™ 350, Novus Biologicals™
SDP

Catalog No. NP247939A30 Shop All R&D Systems Products
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NP247939A30 0.1 mL
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Catalog No. NP247939A30 Supplier Novus Biologicals Supplier No. NBP247939AF350
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Description

Mouse Monoclonal Antibody

Cytokeratin 7 Monoclonal specifically detects Cytokeratin 7 in Human samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunofluorescence.

Specifications

Antigen Cytokeratin 7
Applications Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Classification Monoclonal
Clone KRT7/760
Conjugate Alexa Fluor 350
Dilution Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
Formulation 50 mM sodium borate with 0.05% sodium azide
Gene Alias CK7, CK-7, cytokeratin 7, Cytokeratin-7, K2C7, K7keratin, 55K type II cytoskeletal, keratin 7, keratin, type II cytoskeletal 7, keratin-7, MGC129731, MGC3625, Sarcolectin, SCLkeratin, simple epithelial type I, K7, type II mesothelial keratin K7, Type-II keratin Kb7
Gene Symbols KRT7
Host Species Mouse
Immunogen Recombinant full-length human Cytokeratin 7 protein (Uniprot: P08729)
Purification Method Protein A or G purified
Quantity 0.1 mL
Research Discipline Cytoskeleton Markers
Primary or Secondary Primary
Gene ID (Entrez) 3855.0
Test Specificity It recognizes an intermediate filament protein (IFP) of 55kDa, which is identified as cytokeratin 7. This monoclonal antibody is highly specific to cytokeratin 7 and shows no cross-reaction with other IFPs. Cytokeratin 7 is a basic cytokeratin, which is found in most glandular and transitional epithelia but not in the stratified squamous epithelia. Keratin 7 is expressed in the epithelial cells of ovary, lung, and breast but not of colon, prostate, or gastrointestinal tract. This monoclonal antibody is highly useful in distinguishing ovarian carcinomas (keratin 7+) from colon carcinomas (keratin 7-).
Target Species Human
Content And Storage Store at 4°C in the dark.
Isotype IgG1 κ
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