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Cytokeratin, pan Antibody (KRTL/1077 + KRTH/1076), Novus Biologicals™
SDP

Catalog No. p-5539424 Shop All R&D Systems Products
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NBP24436700 0.02 mg
NBP24436701 0.1 mg
NBP24436702 0.2 mg
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Catalog No. NBP24436700 Supplier Novus Biologicals Supplier No. NBP2443670.02MG
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Description

Mouse Monoclonal Antibody

Ensure accurate, reproducible results in Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence

Cytokeratin, pan Monoclonal specifically detects Cytokeratin, pan in Human, Rat samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

Antigen Cytokeratin, pan
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
Classification Monoclonal
Clone KRTL/1077 + KRTH/1076
Concentration 0.2mg/mL
Conjugate Unconjugated
Dilution Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.25 - 0.5 ug/ml, Immunofluorescence 1 - 2 ug/ml
Formulation 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Host Species Mouse
Immunogen Recombinant human KRT77 and KRT76 protein
Purification Method Protein A or G purified
Quantity 0.02 mg
Regulatory Status RUO
Primary or Secondary Primary
Test Specificity Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, which include CK1, CK3, CK4, CK5, CK6, CK8, CK10, CK14, CK15, CK16, and CK19. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. KRTL/KRTH is a broad spectrum anti pan-cytokeratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It has been used to characterize the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. This antibody stains cytokeratins present in normal and abnormal human tissues and has shown high sensitivity in the recognition of epithelial cells and carcinomas.
Target Species Human, Rat
Content And Storage Store at 4C.
Form Purified
Isotype IgG
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For Research Use Only

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