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EGFR Antibody (31G7 + GFR1195), Alexa Fluor™ 405, Novus Biologicals™
SDP

Catalog No. NB007209 Shop All R&D Systems Products
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NB007209 0.1 mL
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Catalog No. NB007209 Supplier Novus Biologicals Supplier No. NBP247743AF405
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Description

Mouse Monoclonal Antibody

EGFR Monoclonal specifically detects EGFR in Human samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Flow (Cell Surface), Immunofluorescence.

Specifications

Antigen EGFR
Applications Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Classification Monoclonal
Clone 31G7 + GFR1195
Conjugate Alexa Fluor 405
Dilution Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Flow (Cell Surface), Immunofluorescence
Formulation 50mM Sodium Borate with 0.05% Sodium Azide
Gene Alias avian erythroblastic leukemia viral (v-erb-b) oncogene homolog, cell growth inhibiting protein 40, cell proliferation-inducing protein 61, EC 2.7.10, EC 2.7.10.1, epidermal growth factor receptor, epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b)oncogene homolog), ERBB, ErbB1, ERBB1PIG61, HER1, mENA, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1
Gene Symbols EGFR
Host Species Mouse
Immunogen Human EGFR purified from A431 cells (31G7); Recombinant human EGFR protein (GFR1195)
Purification Method Protein A or G purified
Quantity 0.1 mL
Regulatory Status RUO
Research Discipline Cancer, Cell Biology, Cell Cycle and Replication, Cellular Markers, Cellular Signaling, Growth and Development, Hypoxia, Phospho Specific, Signal Transduction, Tumor Suppressors, Tyrosine Kinases
Primary or Secondary Primary
Test Specificity This MAb recognizes a protein of 170kDa, identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, Beta cellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.
Target Species Human
Content And Storage Store at 4°C in the dark.
Isotype IgG2a κ
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